A Study of the Efficacy and Safety of Etrolizumab Treatment in Maintenance of Disease Remission in Ulcerative Colitis (UC) Participants Who Are Naive to Tumor Necrosis Factor (TNF) Inhibitors

Study Purpose

This Phase III, randomized, double-blind, parallel-grouped, placebo-controlled, multicenter study will investigate the efficacy and safety of etrolizumab in maintenance of remission in participants with moderately to severely active UC who are naive to TNF inhibitors and refractory to or intolerant of prior immunosuppressant and/or corticosteroid treatment.

Recruitment Criteria

Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms

Accepts Healthy Volunteers
No

An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes.


An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes.


Searching Both is inclusive of interventional and observational studies.

Study Type
Interventional
Eligible Ages 18 Years - 80 Years
Gender All
More Inclusion & Exclusion Criteria

Inclusion Criteria:

- Moderately to severely active UC as determined by an MCS of 6-12 with an endoscopic subscore greater than or equal to (>=) 2 as determined by the central reading procedure (endoscopy to be performed 4-16 days prior to Day 1), a rectal bleeding subscore >=1, and a stool frequency subscore >= 1 during the screening period (prior to Day 1) - Evidence of UC extending a minimum of 20 centimeters (cm) from the anal verge as determined by baseline endoscopy (flexible sigmoidoscopy or colonoscopy) performed during screening, 4-16 days prior to Day 1 - Naive to treatment with any anti-TNF therapy - Participants must have had an inadequate response, loss of response, or intolerance to prior corticosteroid and/or immunosuppressant treatment - Background regimen for UC may include oral 5-aminosalicylate (5-ASA), oral corticosteroids, budesonide multi-matrix system (MMX), probiotics, azathioprine (AZA), 6-mercaptopurine (6-MP), or methotrexate (MTX) if doses have been stable during the screening period - Use of highly effective contraception - Must have received a colonoscopy within the past year or be willing to undergo a colonoscopy in lieu of a flexible sigmoidoscopy at screening

Exclusion Criteria:

- A history of or current conditions and diseases affecting the digestive tract, such as indeterminate colitis, Crohn's disease, fistulas or abdominal abscesses, colonic mucosal dysplasia, intestinal obstruction, toxic megacolon, or unremoved adenomatous colonic polyps - Prior or planned surgery for UC - Past or present ileostomy or colostomy - Have received non-permitted inflammatory bowel disease (IBD) therapies (including natalizumab, vedolizumab, and efalizumab) as stated in the protocol - Prior treatment with anti-adhesion molecules (such as mucosal addressin cell adhesion molecule [MAdCAM-1]) - Chronic hepatitis B or C infection, human immunodeficiency virus (HIV), or tuberculosis (active or latent)

Trial Details

This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries.

Trial ID:
NCT02165215

Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans.

Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data.

Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs.

Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use.

Phase
Phase 3

The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data.

Lead Sponsor
Hoffmann-La Roche

The person who is responsible for the scientific and technical direction of the entire clinical study.

Principal Investigator
Clinical Trials
Principal Investigator Affiliation Hoffmann-La Roche

Category of organization(s) involved as sponsor (and collaborator) supporting the trial.

Agency Class
Industry
Overall Status Recruiting
Countries Brazil, Canada, Czechia, Denmark, Germany, Hungary, India, Israel, Italy, Mexico, Poland, Slovakia, South Africa, Ukraine, United States

The disease, disorder, syndrome, illness, or injury that is being studied.

Conditions
Colitis, Ulcerative

Contact a Trial Team

If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.

Gastro One, Germantown, Tennessee

Status

Recruiting

Address

Gastro One

Germantown, Tennessee, 38138

Consultants in Gastroenterology, PA, Columbia, South Carolina

Status

Terminated

Address

Consultants in Gastroenterology, PA

Columbia, South Carolina, 29203

Medical University of South Carolina, Charleston, South Carolina

Status

Withdrawn

Address

Medical University of South Carolina

Charleston, South Carolina, 29425

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania

Status

Terminated

Address

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107

PMA Medical Specialists, Limerick, Pennsylvania

Status

Terminated

Address

PMA Medical Specialists

Limerick, Pennsylvania, 19468

Central Sooner Research, Norman, Oklahoma

Status

Recruiting

Address

Central Sooner Research

Norman, Oklahoma, 73012

Toledo Clinic - Inc, Toledo, Ohio

Status

Withdrawn

Address

Toledo Clinic - Inc

Toledo, Ohio, 43623

Cincinnati, Ohio

Status

Terminated

Address

Consultants for Clinical Research Inc.; Cornell Office

Cincinnati, Ohio, 45249

Consultants for Clinical Research Inc., Cincinnati, Ohio

Status

Recruiting

Address

Consultants for Clinical Research Inc.

Cincinnati, Ohio, 45219

Cincinnati, Ohio

Status

Terminated

Address

Consultants for Clinical Research Inc.; Fairfield Office

Cincinnati, Ohio, 45014

Kinston Medical Specialists, Kinston, North Carolina

Status

Recruiting

Address

Kinston Medical Specialists

Kinston, North Carolina, 28501

Chapel Hill, North Carolina

Status

Recruiting

Address

UNC at Chapel Hill - Dpt of Family Medicine; Center for Functional GI and Motility Disorders

Chapel Hill, North Carolina, 27599

Clinical Trials of America Inc, Cary, North Carolina

Status

Withdrawn

Address

Clinical Trials of America Inc

Cary, North Carolina, 27511

Asheville, North Carolina

Status

Completed

Address

Asheville Gastroenterology Associates, P.A.

Asheville, North Carolina, 28801

Rochester, New York

Status

Withdrawn

Address

University of Rochester; Division of Pediatric Pulmonol

Rochester, New York, 14642

New York, New York

Status

Recruiting

Address

Weill Cornell Medical College-New York Presbyterian Hospital

New York, New York, 10021

Concorde Medical Group, New York, New York

Status

Recruiting

Address

Concorde Medical Group

New York, New York, 10016

Allied Gastrointestinal Associates, PA, Voorhees, New Jersey

Status

Terminated

Address

Allied Gastrointestinal Associates, PA

Voorhees, New Jersey, 08043

Las Vegas Medical Research, Las Vegas, Nevada

Status

Withdrawn

Address

Las Vegas Medical Research

Las Vegas, Nevada, 89113

Ehrhardt Clinical Research, LLC, Belton, Missouri

Status

Active, not recruiting

Address

Ehrhardt Clinical Research, LLC

Belton, Missouri, 64012

University of Mississippi Medical Center, Jackson, Mississippi

Status

Completed

Address

University of Mississippi Medical Center

Jackson, Mississippi, 39216

Mayo Clinic - Rochester, Rochester, Minnesota

Status

Terminated

Address

Mayo Clinic - Rochester

Rochester, Minnesota, 55905

University of Minnesota, Minneapolis, Minnesota

Status

Recruiting

Address

University of Minnesota

Minneapolis, Minnesota, 55455

Center for Digestive Health, Troy, Michigan

Status

Recruiting

Address

Center for Digestive Health

Troy, Michigan, 48098

The iResearch Group, LLC, Southfield, Michigan

Status

Terminated

Address

The iResearch Group, LLC

Southfield, Michigan, 58304

Consult and Research Associates, Saint Louis, Michigan

Status

Terminated

Address

Consult and Research Associates

Saint Louis, Michigan, 63122

VA Medical Center, Milwaukee, Michigan

Status

Recruiting

Address

VA Medical Center

Milwaukee, Michigan, 53295

Henry Ford Health System, Detroit, Michigan

Status

Recruiting

Address

Henry Ford Health System

Detroit, Michigan, 48202

Clin. Rsrch Inst. of Michigan, Chesterfield, Michigan

Status

Terminated

Address

Clin. Rsrch Inst. of Michigan

Chesterfield, Michigan, 48047

Commonwealth Clinical Studies, Brockton, Massachusetts

Status

Recruiting

Address

Commonwealth Clinical Studies

Brockton, Massachusetts, 02302

Charm City Research - Prn, Towson, Maryland

Status

Terminated

Address

Charm City Research - Prn

Towson, Maryland, 21204

Chevy Chase Clinical Research, Chevy Chase, Maryland

Status

Terminated

Address

Chevy Chase Clinical Research

Chevy Chase, Maryland, 20815

Louisiana Research Center, LLC, Shreveport, Louisiana

Status

Recruiting

Address

Louisiana Research Center, LLC

Shreveport, Louisiana,

Via Christi Clinic, PA, Wichita, Kansas

Status

Withdrawn

Address

Via Christi Clinic, PA

Wichita, Kansas, 67208

Iowa Digestive Disease Center, Des Moines, Iowa

Status

Recruiting

Address

Iowa Digestive Disease Center

Des Moines, Iowa, 50312

Aquiant Research, New Albany, Indiana

Status

Active, not recruiting

Address

Aquiant Research

New Albany, Indiana, 47150

Medisphere Medical Research Center, Llc, Evansville, Indiana

Status

Withdrawn

Address

Medisphere Medical Research Center, Llc

Evansville, Indiana, 47714

Investigators Research Group, LLC, Brownsburg, Indiana

Status

Terminated

Address

Investigators Research Group, LLC

Brownsburg, Indiana, 46112

Southwest Gastroenterology, Oak Lawn, Illinois

Status

Recruiting

Address

Southwest Gastroenterology

Oak Lawn, Illinois, 60453

Chicago, Illinois

Status

Recruiting

Address

Northwestern University Feinberg School Of Medicine

Chicago, Illinois, 60611

Atlanta Gastroenterology Specialists, PC, Suwanee, Georgia

Status

Withdrawn

Address

Atlanta Gastroenterology Specialists, PC

Suwanee, Georgia, 30024

Marietta, Georgia

Status

Terminated

Address

Gastrointestinal Specialists of Georgia, PC

Marietta, Georgia, 30060

Shafran Gastroenterology Center, Winter Park, Florida

Status

Completed

Address

Shafran Gastroenterology Center

Winter Park, Florida, 32789

Advanced Research Institute, Inc., Trinity, Florida

Status

Recruiting

Address

Advanced Research Institute, Inc.

Trinity, Florida, 34655

Advanced Medical Research Center, Port Orange, Florida

Status

Terminated

Address

Advanced Medical Research Center

Port Orange, Florida, 32127

Med-Care Research, North Miami Beach, Florida

Status

Terminated

Address

Med-Care Research

North Miami Beach, Florida, 33162

FQL Research, LLC, Miramar, Florida

Status

Terminated

Address

FQL Research, LLC

Miramar, Florida, 33025

Regenerate Clinical Trials, Miami, Florida

Status

Completed

Address

Regenerate Clinical Trials

Miami, Florida, 33155

Medical Research Center of Florida, Miami, Florida

Status

Withdrawn

Address

Medical Research Center of Florida

Miami, Florida, 33122

IMIC, Inc, Miami Beach, Florida

Status

Recruiting

Address

IMIC, Inc

Miami Beach, Florida, 33140

Borland-Groover Clinic, Jacksonville, Florida

Status

Terminated

Address

Borland-Groover Clinic

Jacksonville, Florida, 32256

Homestead Medical Research, Homestead, Florida

Status

Terminated

Address

Homestead Medical Research

Homestead, Florida, 33030

GastroCare, Coral Springs, Florida

Status

Terminated

Address

GastroCare

Coral Springs, Florida,

Clearwater, Florida

Status

Recruiting

Address

West Central Gastroenterology d/b/a Gastro Florida

Clearwater, Florida, 33762

Aventura, Florida

Status

Recruiting

Address

Innovative Medical Research of South Florida, Inc.

Aventura, Florida, 33180

Clinical Research of the Rockies, Lafayette, Colorado

Status

Completed

Address

Clinical Research of the Rockies

Lafayette, Colorado, 80026

Colorado Springs, Colorado

Status

Recruiting

Address

Peak Gastroenterology Associates; Gastroenterology

Colorado Springs, Colorado, 80907

Ventura Clinical Trials, Ventura, California

Status

Recruiting

Address

Ventura Clinical Trials

Ventura, California, 93003

Santa Monica Research Institute, Santa Monica, California

Status

Terminated

Address

Santa Monica Research Institute

Santa Monica, California, 90404

San Francisco, California

Status

Recruiting

Address

Uni. of California at San Francisco; Dept Pediatric, Div. of Gastroenterology, Hepatology & Nutri

San Francisco, California, 94158

Clinical Applications Laboratories, Inc., San Diego, California

Status

Recruiting

Address

Clinical Applications Laboratories, Inc.

San Diego, California, 92103

Orange, California

Status

Recruiting

Address

University of California, Irvine Medical Center

Orange, California, 92868

Sutter Gould Medical Foundation, Modesto, California

Status

Terminated

Address

Sutter Gould Medical Foundation

Modesto, California, 95355

Facey Medical Group, Mission Hills, California

Status

Withdrawn

Address

Facey Medical Group

Mission Hills, California, 91345

Gastrointestinal Bioscience, Los Angeles, California

Status

Terminated

Address

Gastrointestinal Bioscience

Los Angeles, California, 90067

Laguna Hills, California

Status

Withdrawn

Address

Therapeutic Research Institute of Orange County

Laguna Hills, California, 92653

La Jolla, California

Status

Withdrawn

Address

University of California San Diego Medical Center

La Jolla, California, 92093-5354

Moore Clinical Trials, LLC, Sherwood, Arkansas

Status

Terminated

Address

Moore Clinical Trials, LLC

Sherwood, Arkansas, 72120

Little Rock, Alaska

Status

Withdrawn

Address

Applied Research Center of Arkansas; Clinical Trials

Little Rock, Alaska, 72212

Digestive Health Specialists, Dothan, Alabama

Status

Terminated

Address

Digestive Health Specialists

Dothan, Alabama, 36305

Decatur Gastroenterology Associates, Decatur, Alabama

Status

Recruiting

Address

Decatur Gastroenterology Associates

Decatur, Alabama, 35601

Medical College of Wisconsin, Inc., Milwaukee, Wisconsin

Status

Terminated

Address

Medical College of Wisconsin, Inc.

Milwaukee, Wisconsin, 53226-3596

Aurora Health Care, Glendale, Wisconsin

Status

Withdrawn

Address

Aurora Health Care

Glendale, Wisconsin, 53212

The Vancouver Clinic, Vancouver, Washington

Status

Terminated

Address

The Vancouver Clinic

Vancouver, Washington, 98604

Rockwood Clinic, PS, Spokane, Washington

Status

Withdrawn

Address

Rockwood Clinic, PS

Spokane, Washington, 99204

Seattle, Washington

Status

Withdrawn

Address

University of Washington School of Medicine

Seattle, Washington, 98104

Seattle, Washington

Status

Not yet recruiting

Address

University of Washington / Harborview Medical Center; University of Washington

Seattle, Washington, 98104

Seattle, Washington

Status

Recruiting

Address

Swedish Medical Center; Swedish Gastroenterology

Seattle, Washington, 98104

Northwest Gastroenterology Associates, Bellevue, Washington

Status

Recruiting

Address

Northwest Gastroenterology Associates

Bellevue, Washington, 98004

Richmond, Virginia

Status

Recruiting

Address

McGuire Research Institute; Gastroenterology

Richmond, Virginia, 23249

Norfolk, Virginia

Status

Terminated

Address

Digestive and Liver Disease Specialists, Ltd.

Norfolk, Virginia, 23502

Charlottesville, Virginia

Status

Terminated

Address

University of Virginia Health Systems; Gastroenterology and Hepatology

Charlottesville, Virginia, 22908

Salt Lake City, Utah

Status

Recruiting

Address

University of Utah School of Medicine; Psychiatry

Salt Lake City, Utah, 84132

Ericksen Research and Development, Clinton, Utah

Status

Completed

Address

Ericksen Research and Development

Clinton, Utah, 84015

Digestive Health Specialists of Tyler, Tyler, Texas

Status

Recruiting

Address

Digestive Health Specialists of Tyler

Tyler, Texas, 75701

Southlake, Texas

Status

Recruiting

Address

Texas Digestive Disease Consultants - Southlake

Southlake, Texas, 76092

San Antonio, Texas

Status

Terminated

Address

Gastroenterology Consultants of San Antonio

San Antonio, Texas, 78233

San Antonio, Texas

Status

Withdrawn

Address

Gastroenterology Research of San Antonio, LLC

San Antonio, Texas, 78229

Houston, Texas

Status

Terminated

Address

University Of Texas Health Science Center Houston

Houston, Texas, 77030

Baylor College of Medicine, Houston, Texas

Status

Terminated

Address

Baylor College of Medicine

Houston, Texas, 77030

Fort Worth, Texas

Status

Withdrawn

Address

University of North Texas Health Science Center

Fort Worth, Texas, 76107

Dallas, Texas

Status

Recruiting

Address

The University of Texas Southwestern Medical Center at Dallas

Dallas, Texas, 75390

Dallas, Texas

Status

Recruiting

Address

Texas Digestive Disease Consultants - Dallas

Dallas, Texas, 75231

Texas Clinical Research Institute, LLC, Arlington, Texas

Status

Withdrawn

Address

Texas Clinical Research Institute, LLC

Arlington, Texas, 76012

International Sites

Vinnytsia, Ukraine

Status

Recruiting

Address

M.I. Pyrogov VRCH Dept of Gastroenterology M.I. Pyrogov VNMU

Vinnytsia, , 21018

Uzhgorod, Ukraine

Status

Recruiting

Address

SI Divisional Clinical Hospital of Uzhgorod Station of ST&BA LZ Dep of Therapy SHEI Uzhgorod NU

Uzhgorod, , 88009

Poltava, Ukraine

Status

Recruiting

Address

M.V. Sklifosovskyi Poltava RCH Dept of Gastroenterology HSEIU UMSA

Poltava, , 36011

Odessa regional clinical Hospital, Odessa, Ukraine

Status

Recruiting

Address

Odessa regional clinical Hospital

Odessa, , 65117

Kyiv, Ukraine

Status

Terminated

Address

LLC Treatment and Diagnostic Center Adonis Plus

Kyiv, , 02002

Kyiv, Ukraine

Status

Terminated

Address

Order of the Red Star MMMCC MMCH Clinic of Gastroenterology

Kyiv, , 01133

Ivano-Frankivsk, Ukraine

Status

Withdrawn

Address

Regional CH Dept of Proctology SHEI Ivano-Frankivsk NMU

Ivano-Frankivsk, , 76018

Ivano-Frankivsk, Ukraine

Status

Terminated

Address

Central City Clinical Hospital Dept of Theraphy No. 2 SHEI Ivano-Frankivsk NMU

Ivano-Frankivsk, , 76005

Uzhgorod, KIEV Governorate, Ukraine

Status

Recruiting

Address

A.Novak Transcarpathian Regional Clinical Hospital

Uzhgorod, KIEV Governorate, 88018

Lviv Regional Clinical Hospital, Lviv, KIEV Governorate, Ukraine

Status

Recruiting

Address

Lviv Regional Clinical Hospital

Lviv, KIEV Governorate, 79010

Kyiv, KIEV Governorate, Ukraine

Status

Recruiting

Address

CI of Kyiv RC Kyiv Regional Clinical Hospital

Kyiv, KIEV Governorate, 04107

Sumy, Kharkiv Governorate, Ukraine

Status

Recruiting

Address

CI of SRC Sumy RCH Dept of Rheumatology Sumy SU MI

Sumy, Kharkiv Governorate, 40022

Emmed Research, Pretoria, South Africa

Status

Recruiting

Address

Emmed Research

Pretoria, , 0084

Dr HR Schneider Practice, Johannesburg, South Africa

Status

Terminated

Address

Dr HR Schneider Practice

Johannesburg, , 2193

Wits Donald Gordon Clinical Trial Site, Johannesburg, South Africa

Status

Withdrawn

Address

Wits Donald Gordon Clinical Trial Site

Johannesburg, , 2041

Dr JP Wright Practice, Cape Town, South Africa

Status

Recruiting

Address

Dr JP Wright Practice

Cape Town, , 7708

Endocare Research, Cape Town, South Africa

Status

Withdrawn

Address

Endocare Research

Cape Town, , 7646

Endomed, s.r.o., Vranov N. Toplou, Slovakia

Status

Recruiting

Address

Endomed, s.r.o.

Vranov N. Toplou, , 093 01

Fakultna nemocnica Nitra, Nitra, Slovakia

Status

Recruiting

Address

Fakultna nemocnica Nitra

Nitra, , 950 01

B+B MED, s.r.o., Kosice, Slovakia

Status

Recruiting

Address

B+B MED, s.r.o.

Kosice, , 040 22

Bratislava, Slovakia

Status

Recruiting

Address

Univerzitna nemocnica Bratislava, Nemocnica Ruzinov

Bratislava, , 826 06

Bratislava, Slovakia

Status

Recruiting

Address

IBDcentrum s.r.o.; Gastroenterologické centrum ASSIDUO a IBD centrum

Bratislava, , 81108

LexMedica Osrodek Badan Klinicznych, Wroclaw, Poland

Status

Recruiting

Address

LexMedica Osrodek Badan Klinicznych

Wroclaw, , 53-114

Nzoz Vivamed, Warszawa, Poland

Status

Recruiting

Address

Nzoz Vivamed

Warszawa, , 03-580

Zespó Przychodni Specjalistycznych PRIMA, Warszawa, Poland

Status

Recruiting

Address

Zespó Przychodni Specjalistycznych PRIMA

Warszawa, , 02-018

Nasz Lekarz Osrodek Badan Klinicznych, Bydgoszcz, Poland

Status

Recruiting

Address

Nasz Lekarz Osrodek Badan Klinicznych

Bydgoszcz, , 85-312

Bydgoszcz, Poland

Status

Withdrawn

Address

Szpital Uniwersytecki; nr 2 im. Dr J. Biziela

Bydgoszcz, , 85-168

Toluca de Lerdo, Mexico

Status

Withdrawn

Address

Centro de Investigacion Torre Medica Sanatorio Toluca

Toluca de Lerdo, , 50120

Monterrey, Mexico

Status

Terminated

Address

Universidad Autonoma De Nuevo Leon, Hospital Universitario Doctor Jose Eleuterio Gonzalez

Monterrey, , 64460

Mexico, Distrito Federal, Mexico

Status

Recruiting

Address

Instituto Nacional de Ciencias; Medicas y Nutricion; Salvador Zubiran

Mexico, Distrito Federal, , 14000

Phylasis Clinicas Research S de RL de CV, Estado de México, Mexico

Status

Recruiting

Address

Phylasis Clinicas Research S de RL de CV

Estado de México, , 54769

Durango, Mexico

Status

Recruiting

Address

Instituto de Investigaciones Aplicadas a la Neurociencia A.C.

Durango, , 34000

Cuernavaca, Mexico

Status

Recruiting

Address

Consultorio Particular del Dr. Miguel Cortes Hernandez

Cuernavaca, , 62290

Acapulco, Mexico

Status

Terminated

Address

Centro de Investigacion; Clinica Del Pacifico

Acapulco, , 39670

Monterrey, Nuevo LEON, Mexico

Status

Recruiting

Address

Centro Regiomontano de Estudios Clínicos Roma S.C.

Monterrey, Nuevo LEON, 64610

Gastro Medical, Mexicali, BAJA California, Mexico

Status

Recruiting

Address

Gastro Medical

Mexicali, BAJA California, 21100

Palermo, Sicilia, Italy

Status

Recruiting

Address

Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone

Palermo, Sicilia, 90127

Rho, Lombardia, Italy

Status

Recruiting

Address

Ospedale di Circolo; Neuropsichiatria Infantile

Rho, Lombardia, 20017

Brescia, Lombardia, Italy

Status

Recruiting

Address

Fondazione Poliambulanza Istituto Ospedaliero

Brescia, Lombardia, 25124

Ospedale Sandro Pertini, Roma, Lazio, Italy

Status

Recruiting

Address

Ospedale Sandro Pertini

Roma, Lazio, 00157

Holy Family Hospital, Nazareth, Israel

Status

Recruiting

Address

Holy Family Hospital

Nazareth, , 16100

Hadassah University Hospital - Ein Kerem, Jerusalem, Israel

Status

Recruiting

Address

Hadassah University Hospital - Ein Kerem

Jerusalem, , 9112001

Shaare Zedek Medical Center, Jerusalem, Israel

Status

Recruiting

Address

Shaare Zedek Medical Center

Jerusalem, , 91031

Wolfson Medical Center, Holon, Israel

Status

Recruiting

Address

Wolfson Medical Center

Holon, , 58100

Rambam Health Care Campus, Haifa, Israel

Status

Terminated

Address

Rambam Health Care Campus

Haifa, , 31096

Bnai Zion Medical Center, Haifa, Israel

Status

Recruiting

Address

Bnai Zion Medical Center

Haifa, , 31048

Assaf Harofeh Medical Center, Beer Yaacov, Israel

Status

Recruiting

Address

Assaf Harofeh Medical Center

Beer Yaacov, , 6093000

Haemek Medical Center, Afula, Israel

Status

Withdrawn

Address

Haemek Medical Center

Afula, , 18101

Poona Hospital and Research Centre, Pune, India

Status

Withdrawn

Address

Poona Hospital and Research Centre

Pune, , 411030

Pune, India

Status

Recruiting

Address

King Edward Memorial Hospital Research Centre

Pune, , 411011

Ruby Hall Clinic, Pune, India

Status

Recruiting

Address

Ruby Hall Clinic

Pune, , 411 001

Kasturba Medical College & Hospital, Mangalore, India

Status

Recruiting

Address

Kasturba Medical College & Hospital

Mangalore, , 575001

S. R. Kalla Memorial General Hospital, Jaipur, India

Status

Recruiting

Address

S. R. Kalla Memorial General Hospital

Jaipur, , 302001

Delhi, India

Status

Recruiting

Address

Govind Ballabh Pant institute of Postgraduate Medical Education & Research

Delhi, , 110002

Jaipur, Rajasthan, India

Status

Withdrawn

Address

Sawai Man Singh Hospital and Medical College

Jaipur, Rajasthan, 302004

Dayanand Medical College and Hospital, Ludhiana, Punjab, India

Status

Recruiting

Address

Dayanand Medical College and Hospital

Ludhiana, Punjab, 141001

Sparsh Hospital, Bhubaneshwar, Odisha, India

Status

Recruiting

Address

Sparsh Hospital

Bhubaneshwar, Odisha, 751007

Midas institute of Gastroenterology, Nagpur, Maharashtra, India

Status

Recruiting

Address

Midas institute of Gastroenterology

Nagpur, Maharashtra, 440012

Rahate surgical Hospital & ICU, Nagpur, Maharashtra, India

Status

Withdrawn

Address

Rahate surgical Hospital & ICU

Nagpur, Maharashtra, 440008

Mumbai, Maharashtra, India

Status

Recruiting

Address

P. D. Hinduja National Hospital & Medical Research Centre

Mumbai, Maharashtra, 400016

Seth Nandlal Dhoot Hospital, Aurangabad, Maharashtra, India

Status

Withdrawn

Address

Seth Nandlal Dhoot Hospital

Aurangabad, Maharashtra, 431210

Bengaluru, Karnataka, India

Status

Recruiting

Address

M. S. Ramaiah Medical College and Hospital

Bengaluru, Karnataka, 560054

Belgaum, Karnataka, India

Status

Recruiting

Address

K.L.E. Society's Dr. Prabhakar Kore Hospital and Medical Research Centre

Belgaum, Karnataka, 590010

Nirmal Hospital, Surat, Gujarat, India

Status

Recruiting

Address

Nirmal Hospital

Surat, Gujarat, 395002

Shree Giriraj Multispeciality Hospital, Rajkot, Gujarat, India

Status

Recruiting

Address

Shree Giriraj Multispeciality Hospital

Rajkot, Gujarat, 360005

Kaizen Hospital, Ahmedabad, Gujarat, India

Status

Withdrawn

Address

Kaizen Hospital

Ahmedabad, Gujarat, 380020

Pushpawati Singhania Research Institute, New Delhi, Delhi, India

Status

Recruiting

Address

Pushpawati Singhania Research Institute

New Delhi, Delhi, 110017

Guwahati, Assam, India

Status

Recruiting

Address

Institute of Digestive and Liver Diseases

Guwahati, Assam, 781006

Hyderabad, Andhra Pradesh, India

Status

Recruiting

Address

Deccan College of Medical Sciences and Allied Hospitals; Department of Gastroenterology

Hyderabad, Andhra Pradesh, 500058

Osmania General Hospital, Hyderabad, Andhra Pradesh, India

Status

Recruiting

Address

Osmania General Hospital

Hyderabad, Andhra Pradesh, 500012

Csongrad Megyei Dr. Bugyi Istvan Korhaz, Szentes, Hungary

Status

Recruiting

Address

Csongrad Megyei Dr. Bugyi Istvan Korhaz

Szentes, , 6600

Szentes, Hungary

Status

Withdrawn

Address

Csongrad Megyei Dr. Bugyi Istvan Korhaz; Belgyogyaszati Osztaly

Szentes, , 6600

Pecsi Tudomanyegyetem, Pecs, Hungary

Status

Recruiting

Address

Pecsi Tudomanyegyetem

Pecs, , 7624

Karolina Korhaz, Mosonmagyaróvár, Hungary

Status

Terminated

Address

Karolina Korhaz

Mosonmagyaróvár, , 9200

Pest Megyei Flor Ferenc Korhaz, Kistarcsa, Hungary

Status

Recruiting

Address

Pest Megyei Flor Ferenc Korhaz

Kistarcsa, , 2084

Gyula, Hungary

Status

Terminated

Address

Békés Megyei Pándy Kálmán Kórház; Onkologiai tanszek

Gyula, , 5703

Bugat Pal Korhaz-Rendelointezet, Gyongyos, Hungary

Status

Recruiting

Address

Bugat Pal Korhaz-Rendelointezet

Gyongyos, , 3200

Debreceni Egyetem Klinikai Kozpont, Debrecen, Hungary

Status

Recruiting

Address

Debreceni Egyetem Klinikai Kozpont

Debrecen, , 4032

Pannónia Klinika Magánorvosi, Budapest, Hungary

Status

Recruiting

Address

Pannónia Klinika Magánorvosi

Budapest, , 1136

Semmelweis Egyetem, Budapest, Hungary

Status

Recruiting

Address

Semmelweis Egyetem

Budapest, , 1083

Budapest, Hungary

Status

Terminated

Address

Clinexpert Egeszsegugyi Szolgaltato es Kereskedelmi Kft

Budapest, , 1033

Szent Margit Hospital; Dept. of Oncology, Budapest, Hungary

Status

Recruiting

Address

Szent Margit Hospital; Dept. of Oncology

Budapest, , 1032

DRC Gyogyszervizsgalo Kozpont Kft, Balatonfured, Hungary

Status

Recruiting

Address

DRC Gyogyszervizsgalo Kozpont Kft

Balatonfured, , 8230

Principal SMO Kft., Baja, Hungary

Status

Terminated

Address

Principal SMO Kft.

Baja, , 6500

Stade, Germany

Status

Terminated

Address

Gastroenterologische Gemeinschaftspraxis Stade

Stade, , 21682

Praxis Dr. med. Volker Aldinger UG, Neustadt, Germany

Status

Terminated

Address

Praxis Dr. med. Volker Aldinger UG

Neustadt, , 67433

Munchen, Germany

Status

Recruiting

Address

Klinikum rechts der Isar der Technischen Universität München

Munchen, , 81675

Muenster, Germany

Status

Terminated

Address

Gastro Campus Research; Praxis am Germania Campus

Muenster, , 48159

Mannheim, Germany

Status

Recruiting

Address

Klinikum Mannheim GmbH Universitätsklinikum

Mannheim, , 68167

Medizinisches Zentrum Klinikum Lueneburg, Lueneburg, Germany

Status

Recruiting

Address

Medizinisches Zentrum Klinikum Lueneburg

Lueneburg, , 21339

Jena, Germany

Status

Recruiting

Address

Universitaetsklinikum Jena; Apotheke des Uniersitätsklinikums Jena

Jena, , 07740

Heidelberg, Germany

Status

Recruiting

Address

Praxis fuer Gastroenterologie, Drs. Ehehalt/ Helmstaedter

Heidelberg, , 69121

Medizinische Hochschule Hannover, Hannover, Germany

Status

Recruiting

Address

Medizinische Hochschule Hannover

Hannover, , 30625

Gastroenterologie, Hamburg, Germany

Status

Withdrawn

Address

Gastroenterologie

Hamburg, , 20249

Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany

Status

Withdrawn

Address

Universitätsklinikum Hamburg-Eppendorf

Hamburg, , 20246

Krankenhaus Martha-Maria Halle-Doelau, Halle (Saale), Germany

Status

Withdrawn

Address

Krankenhaus Martha-Maria Halle-Doelau

Halle (Saale), , 06120

Klinik Johann Wolfgang von Goethe Uni, Frankfurt, Germany

Status

Recruiting

Address

Klinik Johann Wolfgang von Goethe Uni

Frankfurt, , 60590

Kliniken Essen-Mitte, Essen, Germany

Status

Recruiting

Address

Kliniken Essen-Mitte

Essen, , 45136

Universitaetsklinikum Erlangen, Erlangen, Germany

Status

Recruiting

Address

Universitaetsklinikum Erlangen

Erlangen, , 91054

Ellwangen, Germany

Status

Recruiting

Address

Ärztezentrum Ellwangen; Gemeinschaftspraxis

Ellwangen, , 73479

St. Josef-Hospital Universitaetsklinikum, Bochum, Germany

Status

Withdrawn

Address

St. Josef-Hospital Universitaetsklinikum

Bochum, , 44791

Bochum, Germany

Status

Recruiting

Address

Berufsgenossenschaftliches Universitaetsklinikum Bergmannsheil GmbH

Bochum, , 44789

Klinikum Bielefeld gem. GmbH, Bielefeld, Germany

Status

Withdrawn

Address

Klinikum Bielefeld gem. GmbH

Bielefeld, , 33604

Berlin, Germany

Status

Recruiting

Address

Charite - Campus Virchow-Klinikum; Cardiology

Berlin, , 13353

Berlin, Germany

Status

Recruiting

Address

Charite Universitaetsmedizin Berlin - Campus Charite Mitte

Berlin, , 10117

Sygehus Sønderjylland Åbenrå, Åbenrå, Denmark

Status

Terminated

Address

Sygehus Sønderjylland Åbenrå

Åbenrå, , 6200

Regionshospitalet Silkeborg, Silkeborg, Denmark

Status

Recruiting

Address

Regionshospitalet Silkeborg

Silkeborg, , 8600

København Ø, Denmark

Status

Recruiting

Address

Rigshospitalet; Medicinsk gastroenterologisk klinik

København Ø, , 2100

Kolding Sygehus, Kolding, Denmark

Status

Terminated

Address

Kolding Sygehus

Kolding, , 6000

Herlev Hospital, Herlev, Denmark

Status

Recruiting

Address

Herlev Hospital

Herlev, , 2730

Alborg Universitets Hospital, Aalborg, Denmark

Status

Recruiting

Address

Alborg Universitets Hospital

Aalborg, , 9100

Thomayerova nemocnice, Praha 4 - Krc, Czechia

Status

Terminated

Address

Thomayerova nemocnice

Praha 4 - Krc, , 140 59

Nemocnice Na Bulovce, Prague, Czechia

Status

Recruiting

Address

Nemocnice Na Bulovce

Prague, , 180 01

Fakultni nemocnice Olomouc, Olomouc, Czechia

Status

Terminated

Address

Fakultni nemocnice Olomouc

Olomouc, , 775 20

Hepato-Gastroenterologie HK, s.r.o., Hradec Kralove, Czechia

Status

Recruiting

Address

Hepato-Gastroenterologie HK, s.r.o.

Hradec Kralove, , 500 12

Brno, Czechia

Status

Recruiting

Address

Fakultni nemocnice u sv. Anny v Brne; I.Interni kardioangiologicka klinika

Brno, , 65691

CHUM Centre de Recherche - PARENT, Montreal, Quebec, Canada

Status

Withdrawn

Address

CHUM Centre de Recherche - PARENT

Montreal, Quebec, H2W 1T8

Waterloo, Ontario, Canada

Status

Withdrawn

Address

Pharmaceutical Integrated Research Company

Waterloo, Ontario, N2J 1C4

Mount Sinai Hospital, Toronto, Ontario, Canada

Status

Recruiting

Address

Mount Sinai Hospital

Toronto, Ontario, M5G 1Z5

Toronto Sunnybrook Hospital, Toronto, Ontario, Canada

Status

Withdrawn

Address

Toronto Sunnybrook Hospital

Toronto, Ontario, M4N 3M5

London, Ontario, Canada

Status

Completed

Address

London Health Sciences Centre · Victoria Hospital; Research Pharmacy

London, Ontario, N6A 5W9

London, Ontario, Canada

Status

Recruiting

Address

LHSC - University Hospital; Movement Disorders Program

London, Ontario, N6A 5A5

Hamilton, Ontario, Canada

Status

Terminated

Address

McMaster University Health Sciences Center

Hamilton, Ontario, L8N 3Z5

Toronto Digestive Disease Associates, Downsview, Ontario, Canada

Status

Active, not recruiting

Address

Toronto Digestive Disease Associates

Downsview, Ontario, M3N 2V7

Halifax, Nova Scotia, Canada

Status

Recruiting

Address

Queen Elizabeth II Health Sciences Centre; Gastroenterology Research

Halifax, Nova Scotia, B3H 1V7

GI Research Institute, Vancouver, British Columbia, Canada

Status

Recruiting

Address

GI Research Institute

Vancouver, British Columbia, V6Z 2K5

Edmonton, Alberta, Canada

Status

Withdrawn

Address

Zeidler Ledcor Centre - University of Alberta; Division of Gasroenterology

Edmonton, Alberta, T6G 2X8

São Paulo, SP, Brazil

Status

Recruiting

Address

Hospital do Servidor Público Estadual "Francisco Morato de Oliveira" (HSPE)

São Paulo, SP, 04039-901

Sao Paulo, SP, Brazil

Status

Recruiting

Address

Universidade Federal de Sao Paulo - UNIFESP; Neurologia

Sao Paulo, SP, 04024-002

Hospital Sírio-Libanês, Sao Paulo, SP, Brazil

Status

Recruiting

Address

Hospital Sírio-Libanês

Sao Paulo, SP, 01308-050

Santo Andre, SP, Brazil

Status

Recruiting

Address

Centro Multidisciplinar de Estudos Clínicos - CEMEC

Santo Andre, SP, 09190-510

Pesquisare, Santo Andre, SP, Brazil

Status

Recruiting

Address

Pesquisare

Santo Andre, SP, 09080-110

Jaú, SP, Brazil

Status

Recruiting

Address

CECIP - Centro de Estudos Clínicos do Interior Paulista

Jaú, SP, 17210-190

Campinas, SP, Brazil

Status

Recruiting

Address

Allergisa Pesquisa Dermato-Cosmética Ltda

Campinas, SP, 13084-791

Clinica de Neoplasias Litoral, Itajai, SC, Brazil

Status

Recruiting

Address

Clinica de Neoplasias Litoral

Itajai, SC, 88301-220

Hospital São Lucas da PUCRS, Porto Alegre, RS, Brazil

Status

Withdrawn

Address

Hospital São Lucas da PUCRS

Porto Alegre, RS, 90610-000

Hrpc - Ulbratech, Canoas, RS, Brazil

Status

Withdrawn

Address

Hrpc - Ulbratech

Canoas, RS, 92425-900

Porto Alegre, RO, Brazil

Status

Recruiting

Address

Hospital Moinhos de Vento; Instituto de Educação e Pesquisa

Porto Alegre, RO, 90560-030

Hospital Universitario Gaffree e Guinle, Rio de Janeiro, RJ, Brazil

Status

Recruiting

Address

Hospital Universitario Gaffree e Guinle

Rio de Janeiro, RJ, 20270-004

Centro Digestivo de Curitiba, Curitiba, PR, Brazil

Status

Recruiting

Address

Centro Digestivo de Curitiba

Curitiba, PR, 80430-160

Eurolatino Pesquisas Médicas Ltda., Uberlandia, MG, Brazil

Status

Recruiting

Address

Eurolatino Pesquisas Médicas Ltda.

Uberlandia, MG, 38411-186

Fortaleza, CE, Brazil

Status

Recruiting

Address

Hospital Universitario Walter Cantidio - UFC

Fortaleza, CE, 60430-370

Salvador, BA, Brazil

Status

Withdrawn

Address

Centro de Apoio Técnico e Científico Ltda.

Salvador, BA, 41213-006

Salvador, BA, Brazil

Status

Terminated

Address

Hospital Universitário Professor Edgard Santos - Universidade Federal da Bahia

Salvador, BA, 40110-910

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