Accepts Healthy Volunteers
Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms
An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes.
An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes.
Searching Both is inclusive of interventional and observational studies.
|Observational [Patient Registry]|
|Eligible Ages||19 Years - 75 Years|
- - people who receive colonoscopy - people who sign the consent - having inflammatory bowel disease (ulcerative colitis, Crohn's Dz.
Exclusion Criteria:- those aged over 75 years - the disabled - pregnant women - chronic renal diseases (CLcr <50ml/min) - blood coagulopathy (PT INR > 1.5, aPTT > 45 seconds, or platelet count < 50,000/mm) - people who refuse to sign the consent
This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries.
Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans.
Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data.
Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs.
Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use.
The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data.
The person who is responsible for the scientific and technical direction of the entire clinical study.
|Bo-In Lee, MD. Ph.D.|
|Principal Investigator Affiliation||Seoul St. Mary's Hospital|
Category of organization(s) involved as sponsor (and collaborator) supporting the trial.
|Countries||Korea, Republic of|
The disease, disorder, syndrome, illness, or injury that is being studied.
|Inflammatory Bowel Diseases, Irritable Bowel Syndrome|
Inflammatory bowel disease refers to chronic inflammation of the unknown origin that occurs in the intestine. It usually refers to ulcerative colitis and Crohn's disease, which are idiopathic inflammatory bowel diseases. While it had been known to be a common disease in the western world, in recent decades the incidence of ulcerative colitis and Crohn's disease has rapidly increased in Korea as well. Endoscopic examination is a gold standard in order to determine the activity of inflammatory bowel disease, but it is hardly performed due to the cost and time of a test. Therefore, it is necessary to find a blood-based biomarker that replaces endoscopy. The objective of the study is to identify a new inflammatory marker that replaces endoscopy by comparing blood samples of patients with inflammatory bowel disease with those of general controls.
: inflammatory bowel disease
inflammatory bowel disease such as Ulcerative colitis and Crohn's disease
: IBS or Normal Control
irritable bowel syndrome patients normal patients
Other: - inflammatory bowel disease
blood based biomarkers in IBD such as REG3 alpha, serum calprotectin and hs-CRP
Other: - IBS or Normal Control
blood based biomarker compared normal control with IBD
Contact a Trial Team
If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.