A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis
Study Purpose
The purpose of this study is to evaluate the efficacy and safety of guselkumab in participants with moderately to severely active ulcerative colitis (UC).
Recruitment Criteria
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Accepts Healthy Volunteers
Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms |
No |
|
Study Type
An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes. An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes. Searching Both is inclusive of interventional and observational studies. |
Interventional |
| Eligible Ages | 18 Years and Over |
| Gender | All |
Inclusion Criteria:
- Documented diagnosis of ulcerative colitis (UC) - Moderately to severely active UC, defined by modified Mayo score - Demonstrated inadequate response or intolerance to medical therapies specified in the protocol - Screening laboratory test results within the parameters specified in the protocolExclusion Criteria:
- Diagnosis of indeterminate colitis, microscopic colitis, ischemic colitis, or Crohn's disease or clinical findings suggestive of Crohn's disease - UC limited to the rectum only or to less than (<) 20 centimeter (cm) of the colon - Presence of a stoma - Presence or history of a fistula - Receiving prohibited medications and/or treatmentTrial Details
|
Trial ID:
This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries. |
NCT04033445 |
|
Phase
Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans. Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data. Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs. Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use. |
Phase 2/Phase 3 |
|
Lead Sponsor
The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data. |
Janssen Research & Development, LLC |
|
Principal Investigator
The person who is responsible for the scientific and technical direction of the entire clinical study. |
Janssen Research & Development, LLC Clinical Trial |
| Principal Investigator Affiliation | Janssen Research & Development, LLC |
|
Agency Class
Category of organization(s) involved as sponsor (and collaborator) supporting the trial. |
Industry |
| Overall Status | Recruiting |
| Countries | Argentina, Australia, Belgium, Brazil, Bulgaria, Canada, China, Czechia, France, Germany, Hungary, Israel, Italy, Japan, Korea, Republic of, Netherlands, Poland, Portugal, Romania, Russian Federation, Spain, Sweden, Taiwan, Turkey, Ukraine, United Kingdom, United States |
|
Conditions
The disease, disorder, syndrome, illness, or injury that is being studied. |
Ulcerative Colitis |
| Study Website: | View Trial Website |
UC is a chronic disease of the large intestine, in which the lining of the colon becomes inflamed and develops ulcers. Guselkumab is a fully human immunoglobulin G1 lambda monoclonal antibody (mAb) that binds to human interleukin (IL)-23 with high affinity. The study is designed to answer scientific questions pertaining to the efficacy and safety of guselkumab in the treatment of moderately to severely active UC. Overall, the study will evaluate long-term guselkumab treatment. Efficacy, safety, pharmacokinetics (PK), immunogenicity, and biomarkers will be assessed at specified time points.
Arms
Experimental: Induction Study 1: Guselkumab Dose 1
Participants will receive guselkumab dose 1 intravenously (IV) in Induction Study 1. Subsequent study treatment will be determined by the participant's clinical response status at Week 12.
Experimental: Induction Study 1: Guselkumab Dose 2
Participants will receive guselkumab dose 2 IV in Induction Study 1. Subsequent study treatment will be determined by the participant's clinical response status at Week 12.
Placebo Comparator: Induction Study 1: Placebo IV
Participants will receive matching placebo IV in Induction Study 1. Subsequent study treatment will be determined by the participant's clinical response status at Week 12. Clinical nonresponders will be administered guselkumab IV.
Experimental: Induction Study 2: Guselkumab IV
Participants will receive guselkumab IV in Induction Study 2. Subsequent study treatment will be determined by the participant's clinical response status at Week 12.
Placebo Comparator: Induction Study 2: Placebo IV
Participants will receive matching placebo IV in Induction Study 2. Subsequent study treatment will be determined by the participant's clinical response status at Week 12. Clinical nonresponders will be administered guselkumab IV.
Experimental: Maintenance Study: Maintenance Dose Regimen 1
Participants will receive guselkumab maintenance dose regimen 1 subcutaneously (SC) every 4 weeks (q4w).
Experimental: Maintenance Study: Maintenance Dose Regimen 2
Participants will receive guselkumab maintenance dose regimen 2 SC every 8 weeks (q8w).
Placebo Comparator: Maintenance Study: Placebo SC
Participants will receive matching placebo SC q4w.
Interventions
Drug: - Placebo
Participants will receive matching placebo IV or SC.
Drug: - Guselkumab
Participants will receive guselkumab IV or SC.
Contact a Trial Team
If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.
Status
Withdrawn
Address
Alabama Medical Group
Mobile, Alabama, 36608
Status
Not yet recruiting
Address
University of Arizona
Tucson, Arizona, 85724
Status
Not yet recruiting
Address
UC San Diego
La Jolla, California, 92093
Status
Not yet recruiting
Address
Om Research LLC
Lancaster, California, 93534
Status
Not yet recruiting
Address
UCLA
Los Angeles, California, 90095
Status
Withdrawn
Address
Peak Gastroenterology Associates
Colorado Springs, Colorado, 80907
Status
Not yet recruiting
Address
Peak Gastroenterology Associates
Colorado Springs, Colorado, 80920
Status
Not yet recruiting
Address
Florida Research Network, LLC
Gainesville, Florida, 32605
Status
Not yet recruiting
Address
University of Florida
Gainesville, Florida, 32608
Status
Not yet recruiting
Address
Harmony Medical Research Institute, Inc.
Hialeah, Florida, 33016
Status
Withdrawn
Address
River City Clinical Research
Jacksonville, Florida, 32207
Status
Not yet recruiting
Address
UF Health Jacksonville Gastroenterology- Emerson
Jacksonville, Florida, 32207
Status
Recruiting
Address
SIH Research
Kissimmee, Florida, 34741
Status
Not yet recruiting
Address
San Marcus Research Clinic, Inc.
Miami Lakes, Florida, 33014
Status
Not yet recruiting
Address
Columbus Clinical Services LLC
Miami, Florida, 33125
Status
Not yet recruiting
Address
Univ. of South Florida Med. Group
Tampa, Florida, 33606
Status
Withdrawn
Address
GCP Clinical Research
Tampa, Florida, 33609
Status
Not yet recruiting
Address
Alliance Clinical Research
Tampa, Florida, 33615
Status
Not yet recruiting
Address
Emory University
Atlanta, Georgia, 30322
Status
Not yet recruiting
Address
Atlanta Gastroenterology Associates
Atlanta, Georgia, 30342
Status
Not yet recruiting
Address
Atlanta Center For Gastroenterology
Decatur, Georgia, 30033
Status
Not yet recruiting
Address
Gastroenterolgy Associates of Central GA
Macon, Georgia, 31201
Status
Withdrawn
Address
Illinois Gastroenterology Institute, S.C.
Peoria, Illinois, 61606
Status
Withdrawn
Address
Community Clinical Research Center
Anderson, Indiana, 46011
Status
Not yet recruiting
Address
IU Health University Hospital
Indianapolis, Indiana, 46202
Status
Not yet recruiting
Address
Health Science Research Center
Pratt, Kansas, 67124
Status
Not yet recruiting
Address
Tri-State Gastroenterology Assoc
Crestview Hills, Kentucky, 41017
Status
Not yet recruiting
Address
CroNOLA, LLC
Houma, Louisiana, 70360
Status
Withdrawn
Address
Gastroenterologist Lafayette - Jacque F. Noel III MD
Lafayette, Louisiana, 70503-2638
Status
Not yet recruiting
Address
Louisiana Research Center
Shreveport, Louisiana, 71103
Status
Withdrawn
Address
Chevy Chase Clinical Research
Chevy Chase, Maryland, 20815
Status
Withdrawn
Address
Capitol Research
Rockville, Maryland, 20850
Status
Not yet recruiting
Address
Baystate Medical Center
Springfield, Massachusetts, 01199
Status
Not yet recruiting
Address
Clinical Research Institute of Michigan, LLC
Chesterfield, Michigan, 48047
Status
Not yet recruiting
Address
Revive Research Institute
Farmington Hills, Michigan, 48334
Status
Not yet recruiting
Address
Washington University
Saint Louis, Missouri, 63110
Status
Not yet recruiting
Address
Somnos Clinical Research
Lincoln, Nebraska, 68510
Status
Not yet recruiting
Address
United Health Services Hospitals Office of Clinical Trials
Johnson City, New York, 13790
Status
Not yet recruiting
Address
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599
Status
Not yet recruiting
Address
Duke University Hospital Medical Center
Raleigh, North Carolina, 27609
Status
Not yet recruiting
Address
Ohio State University Hospital
Columbus, Ohio, 43210
Status
Not yet recruiting
Address
Great Lakes Medical Research, LLC
Westlake, Ohio, 44145
Status
Not yet recruiting
Address
Digestive Disease Specialists Inc
Oklahoma City, Oklahoma, 73112
Status
Withdrawn
Address
Medical University of South Carolina
Charleston, South Carolina, 29425
Status
Not yet recruiting
Address
Gastroenterology Associates of Orangeburg, SC
Orangeburg, South Carolina, 29118
Status
Not yet recruiting
Address
University of Tennessee
Chattanooga, Tennessee, 37405
Status
Not yet recruiting
Address
Inquest Clinical Research
Baytown, Texas, 77521
Status
Not yet recruiting
Address
Crescent Health Clinical
DeSoto, Texas, 75115
Status
Withdrawn
Address
El Paso Integrated Physicians Group, P.A.
El Paso, Texas, 79912
Status
Not yet recruiting
Address
Baylor College of Medicine
Houston, Texas, 77025
Status
Not yet recruiting
Address
Caprock Gastro Research
Lubbock, Texas, 79424
Status
Not yet recruiting
Address
Tyler Research Institute, LLC
Tyler, Texas, 75701
Status
Not yet recruiting
Address
Gastroenterology Associates of Tidewater
Chesapeake, Virginia, 23320
Status
Not yet recruiting
Address
University of Washington
Seattle, Washington, 98195
Status
Not yet recruiting
Address
Advanced Clinical Research- Spokane Gastroenterology
Spokane, Washington, 99202
Status
Not yet recruiting
Address
Providence Medical Group
Spokane, Washington, 99208
International Sites
Status
Withdrawn
Address
Hospital de Clínicas José de San Martín
Buenos Aires, , 1121
Status
Not yet recruiting
Address
CEMIC (Centro de Educación Médica e Investigaciones Clínicas)
Buenos Aires, , 1431
Status
Not yet recruiting
Address
Cer Instituto Medico
Buenos Aires, , 1878
Status
Not yet recruiting
Address
Cinme - Centro De Investigaciones Metabolicas
Buenos Aires, , C1027AAP
Status
Not yet recruiting
Address
Hospital General de Agudos José Maria Ramos Mejía
Buenos Aires, , C1221ADC
Status
Withdrawn
Address
Expertia S.A
Caba, , C1128AAF
Status
Not yet recruiting
Address
Centro Médico Dra. De Salvo
Caba, , C1426ABP
Status
Not yet recruiting
Address
Clínica Adventista Belgrano
Ciudad De Buenos Aires, , C1430EGF
Status
Withdrawn
Address
Instituto Médico Elsa Pérez I.M.E.P
Ciudadela, , B1702BLP
Status
Not yet recruiting
Address
Sanatorio Duarte Quiroz
Cordoba, , X5002AOQ
Status
Not yet recruiting
Address
Hospital de Alta Complejidad en Red 'El Cruce'
Florencio Varela, , 1888
Status
Withdrawn
Address
HIGA San Martin
La Plata, , 1904
Status
Not yet recruiting
Address
Centro de Investigaciones Medicas Mar Del Plata
Mar Del Plata, , B7600FYK
Status
Not yet recruiting
Address
Fundación de Estudios Clínicos
Rosario, , 2000
Status
Withdrawn
Address
CER San Juan Centro Polivalente de Asistencia e Investigacion Clinica
San Juan, , 05400
Status
Withdrawn
Address
Sanatorio 9 de Julio
San Miguel de Tucuman, , 4000
Status
Withdrawn
Address
Centro Medico Privado de Reumatologia
San Miguel De Tucuman, , T4000AXL
Status
Withdrawn
Address
Sanatorio Vicente Lopez - La Torre
Vicente Lopez, , B1602BWT
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Not yet recruiting
Address
Southern Adelaide Health Network
Bedfford Park, , 5042
Status
Not yet recruiting
Address
Emeritus Research
Camberwell, , 3124
Status
Not yet recruiting
Address
Monash Health
Clayton, , 3156
Status
Withdrawn
Address
St Vincent's hospital
Darlinghurst, , 2010
Status
Not yet recruiting
Address
Western Health
Footscray, , 3011
Status
Not yet recruiting
Address
Frankston Gastrointestinal and Liver Specialists
Frankston, , 3199
Status
Withdrawn
Address
Austin Health
Heidelberg, , 3084
Status
Not yet recruiting
Address
Fiona Stanley Hospital
Murdoch, , 6150
Status
Not yet recruiting
Address
Royal Perth Hospital
Perth, , 6000
Status
Not yet recruiting
Address
Mater Hospital
South Brisbane, , 4101
Status
Not yet recruiting
Address
St John of God Subiaco Hospital
Subiaco, , 6008
Status
Not yet recruiting
Address
Princess Alexandra Hospital
Woolloongabba, , 4102
Status
Not yet recruiting
Address
AZ Sint-Lucas
Brugge, , 8310
Status
Not yet recruiting
Address
Centre Hospitalier De Mouscron
Mouscron, , 7700
Status
Not yet recruiting
Address
Algemeen Ziekenhuis Delta
Roeselare, , 8800
Status
Not yet recruiting
Address
Hospital e Maternidade Celso Pierro
Campinas, , 13590-900
Status
Not yet recruiting
Address
CDC - Centro Digestivo de Curitiba
Curitiba, , 80430-180
Status
Not yet recruiting
Address
Eurolatino Pesquisas Médicas Ltda
Juiz de Fora, , 36033-318
Status
Not yet recruiting
Address
Hospital Sao Vicente de Paulo
Passo Fundo, , 99010-080
Status
Not yet recruiting
Address
NPCRS - Nucleo de Pesquisa Clinica do Rio Grande do Sul
Porto Alegre, , 90430-001
Status
Not yet recruiting
Address
CLIAGEN - Clinica de Atencao em Gastroenterologia Especializada e Nutricao
Salvador, , 41500-300
Status
Not yet recruiting
Address
Onco Star SP Oncologia Ltda
Sao Paulo, , 04532-030
Status
Not yet recruiting
Address
CPQuali Pesquisa Clinica LTDA ME
São Paulo, , 01228-900
Status
Not yet recruiting
Address
Universidade Federal Do Piaui - Campos Universitario
Teresina, , 64049-550
Status
Not yet recruiting
Address
Eurolatino Pesquisas Médicas
Uberlândia, , 38400-368
Status
Not yet recruiting
Address
Medical Centre Asklepii OOD
Dupnitsa, , 2600
Status
Not yet recruiting
Address
Medical Center-1-Sevlievo EOOD
Sevlievo, , 5400
Status
Not yet recruiting
Address
2-nd MHAT
Sofia, , 1202
Status
Not yet recruiting
Address
4th MHAT - Sofia
Sofia, , 1606
Status
Not yet recruiting
Address
DCC Convex EOOD
Sofia, , 1680
Status
Not yet recruiting
Address
Acibadem City Clinic - Oncology Center
Sofia, , 1784
Status
Not yet recruiting
Address
MHAT 'St. Marina' EAD
Varna, , 9010
Status
Not yet recruiting
Address
MHAT Dr Stefan Cherkezov
Veliko Tarnovo, , 5000
Status
Not yet recruiting
Address
GIRI Gastrointestinal Research Institute
Vancouver, British Columbia, V6Z 2K5
Status
Not yet recruiting
Address
Health Sciences Centre
Winnipeg, Manitoba, R3A 1R9
Status
Not yet recruiting
Address
Nova Scotia Health Authority
Halifax, Nova Scotia, B3H 1V7
Status
Not yet recruiting
Address
Mount Sinai Hospital
Toronto, Ontario, M5G 1X5
Status
Not yet recruiting
Address
Hopital Maisonneuve-Rosemont
Montréal, Quebec, H1T 2M4
Status
Not yet recruiting
Address
Royal University Hospital
Saskatoon, Saskatchewan, S7N 0W8
Status
Not yet recruiting
Address
Capital Medical University, Beijing Friendship Hospital
Beijing, , 100050
Status
Not yet recruiting
Address
Peking University Third Hospital
Beijing, , 100191
Status
Not yet recruiting
Address
China-Japan Union Hospital of Jilin University
Changchun, , 130033
Status
Not yet recruiting
Address
The second Xiangya Hospital of Central South University
Changsha, , 200120
Status
Not yet recruiting
Address
The Third Xiangya Hospital of Central Sourth University
Changsha, , 40013
Status
Not yet recruiting
Address
West China Hospital of Sichuan University
Chengdu, , 610041
Status
Not yet recruiting
Address
Daping Hospital
Chongqing, , 400042
Status
Not yet recruiting
Address
The Second Hospital To Dalian Medical University
Dalian, , 116027
Status
Not yet recruiting
Address
First Affiliated Hospital of Gannan Medical University
Ganzhou, , 341000
Status
Not yet recruiting
Address
The First Affiliated Hospital, Sun Yat-sen University
Guangzhou, , 510080
Status
Not yet recruiting
Address
Sun Yat-sen University - The Sixth Affiliated Hospital Guangdong Gastrointestinal Hospital
Guangzhou, , 510610
Status
Not yet recruiting
Address
The First Affiliated Hospital, Zhejiang University College of Medicine
Hangzhou, , 310003
Status
Not yet recruiting
Address
The Second Affiliated Hospital of Zhejiang University
Hangzhou, , 310003
Status
Not yet recruiting
Address
Sir Run Run Shaw Hospital, Zhejiang University
Hangzhou, , 310016
Status
Not yet recruiting
Address
The 1st affiliated hospital of Anhui Medical University
Hefei, , 230022
Status
Not yet recruiting
Address
First Affiliated Hospital of Kunming Medical Unversity
Kunming, , 650032
Status
Not yet recruiting
Address
The First Affiliated Hospital of NanChang University
Nanchang, , 330006
Status
Not yet recruiting
Address
Nanjing Drum Tower Hospital
Nanjing, , 210008
Status
Not yet recruiting
Address
Zhongda Hospital,Southeast University
Nanjing, , 210009
Status
Not yet recruiting
Address
Jiangsu Province Hospital
Nanjing, , 210029
Status
Not yet recruiting
Address
Ruijing Hospital Affiliated To Shanghai Jiaotong University School Of Medicine
Shanghai, , 200025
Status
Not yet recruiting
Address
Shengjing Hospital of China Medical University
Shenyang, , 110004
Status
Not yet recruiting
Address
The Second Hospital Affiliated To Suzhou University
Suzhou, , 215168
Status
Not yet recruiting
Address
The first affiliated hospital of suzhou University
Suzhou, ,
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Not yet recruiting
Address
Tianjin Medical University General Hospital
Tianjin, , 300011
Status
Not yet recruiting
Address
Wuhan Union Hospital
Wuhan, , 430022
Status
Not yet recruiting
Address
Tongji Hospital, Tongji Medical College of HUST
Wuhan, , 430030
Status
Not yet recruiting
Address
Wuxi People's Hospital
Wuxi, , 214023
Status
Not yet recruiting
Address
MUDr. Gregar s.r.o.
Olomouc, , 779 00
Status
Not yet recruiting
Address
Vitkovicka nemocnice a.s.
Ostrava, , 703 84
Status
Not yet recruiting
Address
Artroscan s.r.o.
Ostrava, , 722 00
Status
Not yet recruiting
Address
AXON Clinical s.r.o.
Prague, , 15000
Status
Not yet recruiting
Address
ResTrial GastroEndo, s.r.o
Praha 4, , 143 00
Status
Not yet recruiting
Address
Nemocnice na Homolce
Praha 5, , 150 30
Status
Not yet recruiting
Address
Klinicke centrum ISCARE
Praha 7, , 170 04
Status
Not yet recruiting
Address
CHU caen
Caen, , 14033
Status
Not yet recruiting
Address
CHRU de Lille - Hôpital Claude Huriez
Lille, , 59000
Status
Not yet recruiting
Address
Hopital Saint Eloi
Montpellier, , 34295
Status
Withdrawn
Address
CHU Hotel Dieu, CIC IMAD
Nantes, , 44000
Status
Not yet recruiting
Address
Hopital Saint Antoine
Paris, , 75571
Status
Not yet recruiting
Address
Hopital Haut-Leveque, CMC Magellan
Pessac, , 33604
Status
Not yet recruiting
Address
Centre Hospitalier Lyon Sud
Pierre-Bénite, , 69495
Status
Not yet recruiting
Address
CHU Saint-Etienne - Hôpital Nord
Saint-Priest en Jarez, , 42270
Status
Not yet recruiting
Address
CHU Rangueil
Toulouse, , 31059
Status
Not yet recruiting
Address
CHRU Nancy-Brabois
Vandoeuvre-les-Nancy, , 54511
Status
Not yet recruiting
Address
Universitaetsklinikum Charite, Campus Virchow Klinikum
Berlin, , 13353
Status
Not yet recruiting
Address
Universitätsklinikum Carl-Gustav-Carus Dresden
Dresden, , 01307
Status
Not yet recruiting
Address
Medizinische Hochschule Hannover
Hannover, , 30625
Status
Not yet recruiting
Address
Universitaetsklinikum Heidelberg
Heidelberg, , 69120
Status
Not yet recruiting
Address
Praxisgemeinschaft Jerichow
Jerichow, , 39319
Status
Not yet recruiting
Address
Städtisches Klinikum Lüneburg
Lueneburg, , 21339
Status
Not yet recruiting
Address
Zentrum für Gastroenterologie Saar MVZ GmbH
Saarbrücken, , 66111
Status
Withdrawn
Address
Universitaetsklinikum Tuebingen
Tuebingen, , 72076
Status
Not yet recruiting
Address
Universitaetsklinikum Ulm
Ulm, , 89081
Status
Not yet recruiting
Address
Magyar Honvedseg Egeszsegugyi Kozpont
Budapest, , 1062
Status
Not yet recruiting
Address
Semmelweis Egyetem
Budapest, , 1082
Status
Not yet recruiting
Address
Semmelweis Egyetem, Ii. Belgyogyaszati Klinika
Budapest, , 1088
Status
Not yet recruiting
Address
Vasútegészségügyi Nonprofit Közhasznú Kft., Debreceni Egészs
Debrecen, , 4025
Status
Not yet recruiting
Address
Debreceni Egyetem Klinikai Kozpont
Debrecen, , H-4032
Status
Not yet recruiting
Address
Bugat Pal Korhaz
Gyongyos, , 3200
Status
Not yet recruiting
Address
Szegedi Tud.Egyetem Szent-Gyorgyi Albert Klin. Közp.
Szeged, , 6720
Status
Not yet recruiting
Address
Haemek Medical Center - Afula
Afula, , 1834111
Status
Not yet recruiting
Address
Rambam Medical Center
Haifa, , 31096
Status
Not yet recruiting
Address
Bnai Zion Medical Center
Haifa, , 3449419
Status
Not yet recruiting
Address
Wolfson Medical Center
Holon, , 58100
Status
Not yet recruiting
Address
Shaare Zedek Medical Center
Jerusalem, , 91031
Status
Withdrawn
Address
Hadassah Hebrew University Medical Center
Jerusalem, , 91120
Status
Not yet recruiting
Address
Lev Talpiot Clinic
Jerusalem, , 93624
Status
Not yet recruiting
Address
Galilee Medical Center
Naharia, , 2210001
Status
Not yet recruiting
Address
Policlinico Sant'Orsola Malpighi
Bologna, , 40138
Status
Not yet recruiting
Address
Azienda Ospedaliera Universitaria Careggi
Firenze, , 50134
Status
Not yet recruiting
Address
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milano, , 20122
Status
Not yet recruiting
Address
Ospedale Classificato Equiparato Sacro Cuore Don Calabria di Negrar
Negrar ( Ve), , 37024
Status
Not yet recruiting
Address
Azienda Ospedaliera di Padova
Padova, , 35128
Status
Not yet recruiting
Address
Ospedale Villa Sofia-Cervello
Palermo, , 90146
Status
Not yet recruiting
Address
Azienda Ospedaliera G.Salvini Ospedale di Rho
RHO, ,
Status
Not yet recruiting
Address
Università Campus Biomedico di Roma
Roma, , 00128
Status
Not yet recruiting
Address
Complesso Integrato Columbus
Rome, , 00168
Status
Not yet recruiting
Address
Istituto Clinico Humanitas Rozzano, IRCCS
Rozzano, , 20089
Status
Not yet recruiting
Address
Casa Sollievo della Sofferenza, IRCCS
San Giovanni Rotondo, , 71013
Status
Not yet recruiting
Address
AO Ordine Mauriziano
Torino, , 10128
Status
Not yet recruiting
Address
Tokyo Medical and Dental University Hospital
Bunkyo-ku, , 113-8519
Status
Not yet recruiting
Address
The Jikei University Hospital
Chiba, , 277 -8567
Status
Not yet recruiting
Address
Juntendo University Hospital Urayasu
Chiba, , 279-0021
Status
Not yet recruiting
Address
Fukuoka University Chikushi Hospital
Chikushino, , 818-8502
Status
Not yet recruiting
Address
Ehime Prefectural Central Hospital
Ehime, , 790-0024
Status
Not yet recruiting
Address
Kitakyushu Municipal Medical Center
Fukuoka-ken, , 802-0077
Status
Not yet recruiting
Address
Fukuoka University Hospital
Fukuoka, , 814-0180
Status
Not yet recruiting
Address
Fukushima Medical University Hospital
Fukushima, , 960-1295
Status
Not yet recruiting
Address
Tokai University Hachioji Hospital
Hachioji, , 192-0032
Status
Not yet recruiting
Address
Hirosaki National Hospital
Hirosaki, , 036-8545
Status
Not yet recruiting
Address
Hirosaki University Hospital
Hirosaki, , 036-8563
Status
Not yet recruiting
Address
Kure Kyosai Hospital
Hiroshima, , 737-8505
Status
Not yet recruiting
Address
Asahikawa Medical University Hospital
Hokkaido, , 078-8510
Status
Not yet recruiting
Address
Mito Saiseikai General Hospital
Ibaraki, , 311-4198
Status
Not yet recruiting
Address
Shimane University Hospital
Izumo, , 693-8501
Status
Not yet recruiting
Address
Kagawa Prefectural Central Hospital
Kagawa, , 760-8557
Status
Not yet recruiting
Address
Kagoshima University Hospital
Kagoshima City, , 890-8544
Status
Not yet recruiting
Address
Izuro Imamura Hospital
Kagoshima, , 892-0824
Status
Not yet recruiting
Address
Sameshima Hospital
Kagoshima, , 892-0846
Status
Not yet recruiting
Address
St.Marianna University School of Medicine
Kanagawa, , 216-8511
Status
Not yet recruiting
Address
Matsushima Clinic
Kanagawa, , 220-0045
Status
Not yet recruiting
Address
Kanazawa University Hospital
Kanazawa, , 920-8641
Status
Recruiting
Address
National Hospital Organization Kanazawa Medical Center
Kanazawa, , 920-8650
Status
Not yet recruiting
Address
Nara Medical University Hospital
Kashihara, , 634-8522
Status
Not yet recruiting
Address
Kyushu Rosai Hospital
Kitakyushu, , 800-0296
Status
Not yet recruiting
Address
Aoyama Naika Clinic
Kobe, , 650-0015
Status
Not yet recruiting
Address
Kobe University Hospital
Kobe, , 650-0017
Status
Not yet recruiting
Address
Kochi National Hospital
Kochi, , 780-8077
Status
Not yet recruiting
Address
Yamanashi Prefectural Central Hospital
Kofu, , 400-8506
Status
Not yet recruiting
Address
NHO Kure Medical Center and Chugoku Cancer Center
Kure, , 736-0023
Status
Not yet recruiting
Address
Kyoto Prefectural University of Medicine Hospital
Kyoto, , 602-8566
Status
Not yet recruiting
Address
National Hospital Organization Matsumoto Medical Center
Matsumoto, , 399-8701
Status
Not yet recruiting
Address
Kitasato University Kitasato Institute Hospital
Minato-ku, , 108-8642
Status
Not yet recruiting
Address
Takagi Clinic
Miyagi, , 981-3213
Status
Not yet recruiting
Address
Osaki Citizen Hospital
Miyagi, , 989-6183
Status
Not yet recruiting
Address
Iwate Medical University Hospital
Morioka, , 020-8505
Status
Not yet recruiting
Address
Nagoya University Hospital
Nagoya, , 466-8560
Status
Not yet recruiting
Address
Nagoya City University Hospital
Nagoya, , 467-8602
Status
Not yet recruiting
Address
Nagaoka Chuo General Hospital
Niigata, , 940-8653
Status
Not yet recruiting
Address
Hyogo College of Medicine Hospital
Nishinomiya, , 663-8501
Status
Not yet recruiting
Address
Oita Red Cross Hospital
Oita, , 870-0033
Status
Not yet recruiting
Address
Shinbeppu Hospital
Oita, , 874-8538
Status
Not yet recruiting
Address
Nakagami Hospital
Okinawa, , 904-2195
Status
Not yet recruiting
Address
Kindai University Hospital
Osaka-Sayama, , 589-8511
Status
Not yet recruiting
Address
Osaka Red Cross Hospital
Osaka, , 543-8555
Status
Not yet recruiting
Address
Osaka City University Hospital
Osaka, , 545-8586
Status
Withdrawn
Address
Higashiosaka City Medical Center
Osaka, , 578-8588
Status
Not yet recruiting
Address
Izumiotsu Municipal Hospital
Osaka, , 595-0027
Status
Not yet recruiting
Address
Japan Community Health Care Organization Saitama Medical Center
Saitama, , 330-0074
Status
Not yet recruiting
Address
Hokkaido P.W.F.A.C. Sapporo Kosei General Hospital
Sapporo, , 060-0033
Status
Not yet recruiting
Address
Sapporo Medical University Hospital
Sapporo, , 060-8543
Status
Withdrawn
Address
National Hospital Organization Higashi Ohmi General Medical Center
Shiga, , 527-8505
Status
Not yet recruiting
Address
Tokyo Yamate Medical Center
Shinjuku-ku, , 169-0073
Status
Not yet recruiting
Address
Matsuda Hospital
Shizuoka, , 432-8061
Status
Not yet recruiting
Address
Tokushima University Hospital
Tokushima, , 770-8503
Status
Not yet recruiting
Address
The Jikei University Hospital
Tokyo, , 105-8471
Status
Not yet recruiting
Address
Tokyo Metropolitan Bokutoh Hospital
Tokyo, , 1308575
Status
Not yet recruiting
Address
National Hospital Organization Tokyo Medical Center
Tokyo, , 152-8902
Status
Not yet recruiting
Address
Mie University Hospital
Tsu, , 514-8507
Status
Not yet recruiting
Address
University of Fukui Hospital
Yoshida, , 910-1193
Status
Not yet recruiting
Address
Korea University Ansan Hospital
Ansan-si, , 15355
Status
Not yet recruiting
Address
Inje University Haeundae Paik Hospital
Busan, , 612-896
Status
Not yet recruiting
Address
Yeungnam University Medical Center
Daegu, , 42415
Status
Not yet recruiting
Address
Gachon University Gil Medical Center
Incheon, , 21565
Status
Not yet recruiting
Address
Seoul National University Bundang Hospital
Seongnam-si, , 13620
Status
Not yet recruiting
Address
Kyung Hee University Medical Center
Seoul, , 02447
Status
Not yet recruiting
Address
Severance Hospital, Yonsei University Health System
Seoul, , 03722
Status
Not yet recruiting
Address
Asan Medical Center
Seoul, , 05505
Status
Not yet recruiting
Address
Samsung Medical Center
Seoul, , 06351
Status
Not yet recruiting
Address
The Catholic University of Korea, Seoul St. Mary's Hospital
Seoul, , 06591
Status
Not yet recruiting
Address
Chung-Ang University Hospital
Seoul, , 06973
Status
Not yet recruiting
Address
The Catholic University of Korea St. Vincent's Hospital
Suwon-si, , 16247
Status
Not yet recruiting
Address
Ajou University Hospital
Suwon, , 16499
Status
Not yet recruiting
Address
Onze Lieve Vrouwe Gasthuis
Amsterdam, , 1091 AC
Status
Not yet recruiting
Address
Radboudumc
Nijmegen, , 6525 GA
Status
Not yet recruiting
Address
Gastromed Kralisz Romatowski Stachurska Sp. j.
Bialystok, , 15-322
Status
Not yet recruiting
Address
Szpital Uniwersytecki nr 2 im. dr. Jana Biziela w Bydgoszczy
Bydgoszcz, , 85-164
Status
Not yet recruiting
Address
Centrum medyczne plejady
Krakow, , 30-363
Status
Recruiting
Address
Centrum Medyczne Promed
Krakow, , 31-513
Status
Withdrawn
Address
Centrum Medyczne Szpital św. Rodziny
Lodz, , 90-302
Status
Not yet recruiting
Address
Gastromed ZOZ
Lublin, , 20-583
Status
Not yet recruiting
Address
Medicome Sp z o.o.
Oswiecim, , 32-600
Status
Not yet recruiting
Address
Centrum Medyczne Medyk
Rzeszow, , 35-326
Status
Not yet recruiting
Address
Endoskopia Sp z o.o.
Sopot, , 81-756
Status
Not yet recruiting
Address
Twoja Przychodnia - Szczecinskie Centrum Medyczne
Szczecin, , 71-434
Status
Not yet recruiting
Address
GASTROMED Kopon, Zmudzinski i wspolnicy SP.j., Specjalistyczne Centrum Gastrologii i Endoskopii
Torun, , 87-100
Status
Withdrawn
Address
H-T Centrum Medyczne Endoterapia
Tychy, , 43-100
Status
Not yet recruiting
Address
WIP Warsaw IBD Point Profesor Kierkus
Warszawa, , 00-728
Status
Not yet recruiting
Address
Centralny Szpital Kliniczny Mswia
Warszawa, , 02-507
Status
Not yet recruiting
Address
NZOZ Vivamed
Warszawa, , 03-580
Status
Not yet recruiting
Address
Wojskowy Instytut Medyczny
Warszawa, , 04-349
Status
Not yet recruiting
Address
Melita Medical Sp. z o.o.
Wroclaw, , 50-449
Status
Not yet recruiting
Address
Centrum Medyczne WroMedica
Wroclaw, , 51-685
Status
Not yet recruiting
Address
ETG Zamosc
Zamosc, , 22-400
Status
Not yet recruiting
Address
Centro Hospitalar e Universitário de Coimbra, EPE
Coimbra, , 3000-075
Status
Not yet recruiting
Address
Centro Hospitalar do Porto, EPE
Porto, , 4099-001
Status
Not yet recruiting
Address
Centro Hospitalar de São João, EPE
Porto, , 4200-319
Status
Not yet recruiting
Address
Centro Hospitalar de Entre o Douro e Vouga, E.P.E
Santa Maria da Feira, , 4520-211
Status
Not yet recruiting
Address
Centro Hospitalar de Tondela Viseu, EPE
Viseu, , 3504-509
Status
Not yet recruiting
Address
Centrul Medical SANA
Bucharest, , 11025
Status
Not yet recruiting
Address
Spitalul Clinic CF2
Bucharest, , 12244
Status
Not yet recruiting
Address
HIFU Terramed Conformal
Bucharest, , 31864
Status
Not yet recruiting
Address
MedLife Grivita
Bucuresti, , 010719
Status
Not yet recruiting
Address
Spitalul Clinic Colentina
Bucuresti, , 020125
Status
Not yet recruiting
Address
Spital Premiere
Timisoara, , 300645
Status
Not yet recruiting
Address
LLC Evimed
Chelyabinsk, , 454048
Status
Not yet recruiting
Address
Chelyabinck Regional Clinical Hospital
Chelyabinsk, , 454076
Status
Not yet recruiting
Address
OOO MO New Hospital
Ekaterinburg, , 620109
Status
Not yet recruiting
Address
Irkutsk State Medical Academy of Postgraduate Education
Irkutsk, , 664079
Status
Not yet recruiting
Address
Kazan State Medical University
Kazan, , 420012
Status
Not yet recruiting
Address
GUZ of Moscow City Clinical Hospital #24
Moscow, , 127015
Status
Not yet recruiting
Address
Road Clinical Hospital at the Nizhny Novgorod Station of the Russian Railways
Nizhniy Novgorod, , 603140
Status
Not yet recruiting
Address
Medical Center 'SibNovoMed' LLC
Novosibirsk, , 630005
Status
Not yet recruiting
Address
State Scientific-research Institute of Psysiology and Basic Medicine
Novosibirsk, , 630117
Status
Not yet recruiting
Address
Rostov State Medical University
Rostov-On-Don, , 344022
Status
Not yet recruiting
Address
Elizavetinskaya hospital
Saint Petersburg, , 195257
Status
Not yet recruiting
Address
All-Russian Center of Emergency and Radiation Medicine MCRS
Saint-Petersburg, , 194044
Status
Not yet recruiting
Address
Eco-safety Ltd
Saint-Petersburg, , 196143
Status
Not yet recruiting
Address
Medical University Reaviz
Samara, , 443001
Status
Not yet recruiting
Address
NUZ 'Railway Clinical Hospital on Samara station of LLC 'Russian Railways'
Samara, , 443041
Status
Not yet recruiting
Address
Regional Hospital of War Veterans
Saratov, , 410053
Status
Not yet recruiting
Address
International Medical Centre SOGAZ
St-Petersburg, , 191186
Status
Not yet recruiting
Address
Regional Clinical Hospital
Tver, , 170036
Status
Not yet recruiting
Address
GBUZ Respublican Clinical Hospital n.a. GG Kuvatova
Ufa, , 450005
Status
Not yet recruiting
Address
City Clinical Hospital # 21
Ufa, , 450071
Status
Not yet recruiting
Address
Ulyanovsk Regional Clinical Hospital
Ulyanovsk, , 432063
Status
Not yet recruiting
Address
Regional Clinical Hospital
Yaroslavl, , 150062
Status
Not yet recruiting
Address
Hosp. Univ. Germans Trias I Pujol
Badalona, , 08916
Status
Not yet recruiting
Address
Hosp. Univ. Dr. Josep Trueta
Girona, , 17007
Status
Not yet recruiting
Address
Hosp. Univ. La Paz
Madrid, , 28046
Status
Not yet recruiting
Address
Hosp. Univ. Marques de Valdecilla
Santander, , 39008
Status
Not yet recruiting
Address
Hosp. Virgen Del Rocio
Sevilla, , 41013
Status
Not yet recruiting
Address
Hosp. Ntra. Sra. de Valme
Sevilla, , 41014
Status
Withdrawn
Address
Hosp. Univ. Miguel Servet
Zaragoza, , 50009
Status
Not yet recruiting
Address
Södra Älvsborgs Sjukhus, Kirurgkliniken, Borås
Boras, , SE-501 82
Status
Not yet recruiting
Address
Karolinska Universitetssjukhuset
Stockholm, , SE-171 76
Status
Not yet recruiting
Address
Uppsala University
Uppsala, , SE-75185
Status
Not yet recruiting
Address
Chang-Hua Christian Hospital
Changhua, , 50006
Status
Not yet recruiting
Address
Taichung Veterans General Hospital
Taichung, , 40705
Status
Not yet recruiting
Address
National Taiwan University Hospital
Taipei, , 10002
Status
Not yet recruiting
Address
Chang-Gung Memorial Hospital, LinKou Branch
Taoyuan, , 33305
Status
Withdrawn
Address
Ankara Gulhane Training and Research Hospital
Ankara, , 06010
Status
Not yet recruiting
Address
Ankara University
Ankara, , 06100
Status
Not yet recruiting
Address
Dışkapı Yıldırım Beyazıd Training and Research Hospital
Ankara, , 06110
Status
Not yet recruiting
Address
Hacettepe University Hospital
Ankara, , 06230
Status
Not yet recruiting
Address
Gazi University Hospital
Ankara, , 06560
Status
Not yet recruiting
Address
Ankara Sehir Hastanesi
Ankara, , 06800
Status
Not yet recruiting
Address
Istanbul University Cerrahpasa Medical Faculty
Istanbul, , 34098
Status
Not yet recruiting
Address
Acibadem Kozyatagi Hospital
Istanbul, , 34734
Status
Not yet recruiting
Address
BAU Medical Park Goztepe Hospital
Istanbul, , 34742
Status
Not yet recruiting
Address
Dokuz Eylül University Medical Faculty
Izmir, , 35330
Status
Not yet recruiting
Address
Kocaeli University Medical Faculty
Kocaeli, , 41380
Status
Not yet recruiting
Address
Mersin University Medical Faculty Hospital
Mersin, , 33110
Status
Not yet recruiting
Address
Communal Nonprofit Enterprise 'City Clinical Hospital # 2 N.A. Prof. O.O. Shalimov'
Kharkiv, , 61037
Status
Not yet recruiting
Address
SI 'L.T. Maloyi National Institute of Therapy of National Academy of Medical Sciences of Ukraine'
Kharkiv, , 61039
Status
Not yet recruiting
Address
Municipal Institution 'Kherson City Clinical Hospital n.a. Y.Y.Karabelesh'
Kherson, , 73003
Status
Not yet recruiting
Address
Kyiv City Clinical Hospital #18
Kyiv, , 01030
Status
Not yet recruiting
Address
Private Clinic OK Clinic
Kyiv, , 02091
Status
Not yet recruiting
Address
Lviv Clinical Hospital on Railway Transport of Affiliate Healthcare center of JSC Ukrainian Railway
Lviv, , 79007
Status
Not yet recruiting
Address
Communal Nonprofit Enterprise of Lviv Regional Council 'Lviv Regional Clinical Hospital'
Lviv, , 79010
Status
Not yet recruiting
Address
Municipal Non-profit Enterprise 'Odesa Regional Clinical Hospital' Odesa Regional Council
Odesa, , 65025
Status
Not yet recruiting
Address
Sumy State University, Sumy Regional Clinical Hospital
Sumy, , 40022
Status
Not yet recruiting
Address
Municipal institution of Tepnopil Regional Council 'Ternopil University Hospital'
Ternopil, , 46002
Status
Not yet recruiting
Address
MNCE 'Zakarpatska Regional Clinical Hospital named after A. Novak' of Zakarpatska Regional Council
Uzhgorod, , 88000
Status
Not yet recruiting
Address
Medical Center Ltd 'Health Clinic', Department Of General Therapy
Vinnytsya, , 21009
Status
Not yet recruiting
Address
Vinnitsia Regional Clinical Hospital n.a. M. I. Pyrogov
Vinnytsya, , 21018
Status
Not yet recruiting
Address
Addenbrooke's Hospital
Cambridge, , CB2 0QQ
Status
Not yet recruiting
Address
Glasgow Royal Infirmary
Glasgow, , G4 0SF
Status
Withdrawn
Address
Royal Free Hospital
London, , NW3 2QG
Status
Not yet recruiting
Address
Guy's and St Thomas' Hospital
London, , SE1 7EH
Status
Not yet recruiting
Address
Chelsea And Westminster Hospital
London, , SW109NH
Status
Not yet recruiting
Address
St George's Hospital
London, , SW17 0QT
Status
Not yet recruiting
Address
Whiston Hospital
Prescot, , L35 5DR
