A Study of LY3471851 in Adult Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Study Purpose

The reason for this study is to determine if the study drug LY3471851 is safe and effective in adult participants with active ulcerative colitis (UC). The study will last about 52 weeks.

Recruitment Criteria

Accepts Healthy Volunteers

Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms

No
Study Type

An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes.


An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes.


Searching Both is inclusive of interventional and observational studies.

Interventional
Eligible Ages 18 Years - 75 Years
Gender All
More Inclusion & Exclusion Criteria

Inclusion Criteria:

  • - Have moderately to severely active ulcerative colitis (UC) as defined by a modified Mayo score (MMS) of 4 to 9 with an endoscopic subscore (ES) ≥2, with endoscopy performed within 14 days before baseline.
  • - Have evidence of UC extending proximal to the rectum (with ≥15 centimeters (cm) of involved colon).
  • - Have up-to-date colorectal cancer surveillance performed according to local standard.
  • - Participants are either one of the following: - Have failed conventional treatments including inability to tolerate oral or intravenous corticosteroids or immunomodulators (6-mercaptopurine or azathioprine or methotrexate), or history of corticosteroid dependence (an inability to successfully taper corticosteroids without return of UC) and neither failed or demonstrated intolerance to advanced therapy (eg, tumor necrosis factor (TNF) antagonists, anti-integrin therapies, anti-IL12/23p40 therapies, Janus kinase (JAK) inhibitor) OR, - Have failed advanced therapies such as treatment with 1 or more advance therapies (eg, tumor necrosis factor [TNF] antagonists, anti-integrin therapies, anti-IL12/23p40 therapies, Janus kinase [JAK] inhibitor) at doses approved for the treatment of UC with documented history of failure to respond to or tolerate such treatment.
  • - Have had an established diagnosis of UC of ≥3 months in duration before baseline which includes endoscopic evidence of UC and a histopathology report that supports a diagnosis of UC.
Supportive endoscopy and histopathology reports must be available in the source documents.
  • - Women of child-bearing potential (WOCBP) must test negative for pregnancy as indicated by a negative serum pregnancy test at the screening visit followed by a negative urine pregnancy test within 24 hours prior to first exposure to study drug.

Exclusion Criteria:

  • - Have been diagnosed with indeterminant colitis, proctitis (colitis limited to the rectum only; less than 15 centimeter (cm) from the anal verge or Crohn's disease.
  • - Have received any of the following for treatment of UC: cyclosporine, tacrolimus, mycophenolate mofetil or thalidomide within 2 weeks of screening, rectally administered corticosteroids or 5-aminosalicylic acid treatments within 2 weeks of screening.
  • - Have had or will need abdominal surgery for UC (for example, subtotal colectomy).
  • - Have failed 3 or more classes of advanced therapies approved for treatment of UC (eg, tumor necrosis factor [TNF] antagonists, anti-integrin therapies, anti-IL12/23p40 therapies, Janus kinase [JAK] inhibitor).
  • - Have evidence of toxic megacolon, intra-abdominal abscess, or stricture/stenosis within the small bowel or colon.
  • - Have any history or evidence of cancer of the gastrointestinal tract.
  • - Have myocardial infarction, unstable ischemic heart disease, stroke or heart failure within 12 months prior to screening.

Trial Details

Trial ID:

This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries.

NCT04677179
Phase

Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans.

Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data.

Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs.

Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use.

Phase 2
Lead Sponsor

The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data.

Eli Lilly and Company
Principal Investigator

The person who is responsible for the scientific and technical direction of the entire clinical study.

Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)
Principal Investigator Affiliation Eli Lilly and Company
Agency Class

Category of organization(s) involved as sponsor (and collaborator) supporting the trial.

Industry
Overall Status Recruiting
Countries Argentina, Australia, Belgium, Brazil, Canada, China, Czechia, France, Georgia, Hungary, India, Israel, Japan, Korea, Republic of, Latvia, Poland, Romania, Russian Federation, Slovakia, Ukraine, United Kingdom, United States
Conditions

The disease, disorder, syndrome, illness, or injury that is being studied.

Colitis, Ulcerative
Study Website: View Trial Website
Additional Details

In stage 1, two doses (high and low) of LY3471851 will be compared to placebo. In stage 2, up to two additional doses (to be confirmed) of LY3471851 will be compared to placebo. LY3471851 (NKTR-358) is a potential first-in-class therapeutic that may address an underlying immune system imbalance in people with many autoimmune conditions. It targets the interleukin (IL-2) receptor complex in the body in order to stimulate proliferation of inhibitory immune cells known as regulatory T cells. By activating these cells, LY3471851 may act to bring the immune system back into balance.

Arms & Interventions

Arms

Experimental: LY3471851 (High Dose)

Stage 1 LY3471851 given subcutaneously (SC) Stage 2 LY3471851 multiple doses to be confirmed

Experimental: LY3471851 (Low Dose)

Stage 1 LY3471851 given subcutaneously (SC) Stage 2 LY3471851 multiple doses to be confirmed

Placebo Comparator: Placebo

Stage 1 Placebo given SC Stage 2 Placebo given SC

Interventions

Drug: - LY3471851

administered SC

Drug: - LY3471851

administered SC

Drug: - Placebo

administered SC

Contact a Trial Team

If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.

Dedicated Clinical Research, Litchfield Park, Arizona

Status

Recruiting

Address

Dedicated Clinical Research

Litchfield Park, Arizona, 85340

I.H.S. Health, LLC, Kissimmee, Florida

Status

Active, not recruiting

Address

I.H.S. Health, LLC

Kissimmee, Florida, 34741

Pensacola, Florida

Status

Completed

Address

Gastroenterology Associates of Pensacola, PA

Pensacola, Florida, 32503

Atlantic Digestive Health Institute, Morristown, New Jersey

Status

Recruiting

Address

Atlantic Digestive Health Institute

Morristown, New Jersey, 07960

Biopharma Informatic, LLC, Houston, Texas

Status

Completed

Address

Biopharma Informatic, LLC

Houston, Texas, 77084

Southern Star Research Institute, LLC, San Antonio, Texas

Status

Active, not recruiting

Address

Southern Star Research Institute, LLC

San Antonio, Texas, 78229

Care Access Research - Ogden, Ogden, Utah

Status

Recruiting

Address

Care Access Research - Ogden

Ogden, Utah, 84403

International Sites

DOM- Centro de Reumatologia, Caba, Buenos Aires, Argentina

Status

Completed

Address

DOM- Centro de Reumatologia

Caba, Buenos Aires, 1111

Caba, Buenos Aires, Argentina

Status

Recruiting

Address

Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno" CEMIC

Caba, Buenos Aires, C1431FWO

Ciudad Autonoma De Buenos Air, Buenos Aires, Argentina

Status

Completed

Address

Mautalen Salud e Investigacion-Centro de Osteopatías Médicas

Ciudad Autonoma De Buenos Air, Buenos Aires, C1128AAF

Centro Médico Privado de Reumatología, Tucumán, Argentina

Status

Completed

Address

Centro Médico Privado de Reumatología

Tucumán, , T4000AXL

Concord Repatriation General Hospital, Concord, New South Wales, Australia

Status

Completed

Address

Concord Repatriation General Hospital

Concord, New South Wales, 2139

Paratus Clinical Research Brisbane, Albion, Queensland, Australia

Status

Recruiting

Address

Paratus Clinical Research Brisbane

Albion, Queensland, 4010

Mater Adult Hospital Brisbane, South Brisbane, Queensland, Australia

Status

Recruiting

Address

Mater Adult Hospital Brisbane

South Brisbane, Queensland, 4700

St. Vincent's Hospital, Fitzroy, Victoria, Australia

Status

Recruiting

Address

St. Vincent's Hospital

Fitzroy, Victoria, 3065

Brussels, Bruxelles-Capitale, Région De, Belgium

Status

Recruiting

Address

Université Libre de Bruxelles - Hôpital Erasme

Brussels, Bruxelles-Capitale, Région De, 1070

Tournai, Wallonne, Région, Belgium

Status

Recruiting

Address

Centre Hospitalier de Wallonie Picarde - Site Notre Dame

Tournai, Wallonne, Région, 7500

AZ Maria Middelares, Gent, Belgium

Status

Recruiting

Address

AZ Maria Middelares

Gent, , 9100

Chronos Pesquisa Clínica, Brasília, Distrito Federal, Brazil

Status

Recruiting

Address

Chronos Pesquisa Clínica

Brasília, Distrito Federal, 72145-450

Porto Alegre, Rio Grande Do Sul, Brazil

Status

Recruiting

Address

Nucleo de Pesquisa Clínica do Rio Grande do Sul-NPCRS

Porto Alegre, Rio Grande Do Sul, 90430-001

Campinas, Sao Paulo, Brazil

Status

Recruiting

Address

HMCP - Hospital e Maternidade Celso Pierro - PUC-Campinas

Campinas, Sao Paulo, 13060-904

Pesquisare, Santo Andre, Sao Paulo, Brazil

Status

Recruiting

Address

Pesquisare

Santo Andre, Sao Paulo, 09080-110

Sao Paulo, SP, Brazil

Status

Recruiting

Address

Instituto de Assistencia Medica ao Servidor Publico Estudo Estadual

Sao Paulo, SP, 04039-004

Botucatu, São Paulo, Brazil

Status

Recruiting

Address

Upeclin - Unidade de Pesquisa Clínica da Faculdade de Medicina de Botucatu - UNESP

Botucatu, São Paulo, 18618-687

São Bernardo do Campo, São Paulo, Brazil

Status

Recruiting

Address

CEMEC - Centro Multidisciplinar de Estudos Clinicos EPP Ltda

São Bernardo do Campo, São Paulo, 09715-090

Hepatogastro, Sao Paulo, Brazil

Status

Recruiting

Address

Hepatogastro

Sao Paulo, , 04543-001

Edmonton, Alberta, Canada

Status

Recruiting

Address

Gastroenterology and internal medicine research institute

Edmonton, Alberta, T5R 1W2

Halifax, Nova Scotia, Canada

Status

Recruiting

Address

Gastroenterology Research, Nova Scotia Health Authority

Halifax, Nova Scotia, B3H2Y9

Greenfield Park, Quebec, Canada

Status

Recruiting

Address

CISSS de la Montérégie - Centre Hôpital Charles-Le Moyne

Greenfield Park, Quebec, J4V2H1

McGill University, Montreal, Quebec, Canada

Status

Not yet recruiting

Address

McGill University

Montreal, Quebec, H3G 1A4

HefeiCity, Anhui, China

Status

Not yet recruiting

Address

The First Affiliated Hospital of Anhui Medical University

HefeiCity, Anhui, 230022

Guangzhou, Guangdong, China

Status

Recruiting

Address

First affiliated Hospital of Sun Yat-Sen University

Guangzhou, Guangdong, 510080

Guangzhou, Guangdong, China

Status

Recruiting

Address

The Sixth Affiliated Hospital, Sun Yat-Sen University

Guangzhou, Guangdong, 510655

Wu Han, Hubei, China

Status

Recruiting

Address

Tongji Hosp Tongji Med Col Huazhong Univ of Sci & Tech

Wu Han, Hubei, 430030

Wuhan, Hubei, China

Status

Recruiting

Address

Union Hospital Tongji Medical College Huazhong University of Science and Technology

Wuhan, Hubei, 430022

Nanchang, Jiangxi, China

Status

Not yet recruiting

Address

The First Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, 330006

Taian City Central Hospital, Taian, Shandong, China

Status

Not yet recruiting

Address

Taian City Central Hospital

Taian, Shandong, 271000

Shanghai, Shanghai, China

Status

Recruiting

Address

Shanghai Jiaotong University School of Medicine Ruijin Hospital

Shanghai, Shanghai, 200025

Sir Run Run Shaw Hospital, Hangzhou, Zhejiang, China

Status

Recruiting

Address

Sir Run Run Shaw Hospital

Hangzhou, Zhejiang, 310018

A-Shine, Pilsen, Plzeň-město, Czechia

Status

Active, not recruiting

Address

A-Shine

Pilsen, Plzeň-město, 312 00

MUDr. Gregar, s.r.o., Olomouc, Czechia

Status

Completed

Address

MUDr. Gregar, s.r.o.

Olomouc, , 779 00

PreventaMed, s.r.o., Olomouc, Czechia

Status

Recruiting

Address

PreventaMed, s.r.o.

Olomouc, , 779 00

I. Interni klinika FN Plzen, Plzen-Lochotin, Czechia

Status

Recruiting

Address

I. Interni klinika FN Plzen

Plzen-Lochotin, , 304 60

Nemocnice Slaný, Slany, Czechia

Status

Active, not recruiting

Address

Nemocnice Slaný

Slany, , 274 01

CHU De Grenoble Hopital Albert Michallon, Grenoble Cedex 09, France

Status

Recruiting

Address

CHU De Grenoble Hopital Albert Michallon

Grenoble Cedex 09, , 38043

Centre Hospitalier de Mont de Marsan, Mont-de-Marsan Cedex, France

Status

Recruiting

Address

Centre Hospitalier de Mont de Marsan

Mont-de-Marsan Cedex, , 40024

Tbilisi, Georgia

Status

Recruiting

Address

Acad. F. Todua Medical Center - Research Institute of Clinical Medicine

Tbilisi, , 0112

Medical Center: Medinvestment, Tbilisi, Georgia

Status

Recruiting

Address

Medical Center: Medinvestment

Tbilisi, , 0186

Clinexpert SMO, Budapest, Hungary

Status

Active, not recruiting

Address

Clinexpert SMO

Budapest, , 1033

Óbudai Egészségügyi Centrum, Budapest, Hungary

Status

Recruiting

Address

Óbudai Egészségügyi Centrum

Budapest, , 1036

Bugát Pál Kórház, Gyöngyös, Hungary

Status

Completed

Address

Bugát Pál Kórház

Gyöngyös, , 3200

CLINFAN Szolgáltató Kft, Szekszard, Hungary

Status

Active, not recruiting

Address

CLINFAN Szolgáltató Kft

Szekszard, , 7100

Shree Giriraj Multispeciality Hospital, Rajkot, Gujarat, India

Status

Not yet recruiting

Address

Shree Giriraj Multispeciality Hospital

Rajkot, Gujarat, 360004

Surat, Gujarat, India

Status

Not yet recruiting

Address

Gujarat Hospital - Gastro and Vascular Centre

Surat, Gujarat, 395009

Kingsway Hospital, Nagpur, Maharashtra, India

Status

Not yet recruiting

Address

Kingsway Hospital

Nagpur, Maharashtra, 440001

Midas Multispeciality Hospital Pvt.Ltd., Nagpur, Maharashtra, India

Status

Not yet recruiting

Address

Midas Multispeciality Hospital Pvt.Ltd.

Nagpur, Maharashtra, 440010

Jaipur, Rajasthan, India

Status

Not yet recruiting

Address

SR Kalla Memorial Gastro & General Hospital

Jaipur, Rajasthan, 302006

Apollo Speciality Hospital - Teynampet, Chennai, Tamil Nadu, India

Status

Not yet recruiting

Address

Apollo Speciality Hospital - Teynampet

Chennai, Tamil Nadu, 600035

Chandigarh, India

Status

Not yet recruiting

Address

Postgraduate Institute of Medical Education & Research

Chandigarh, , 160012

Gandhi Hospital, Telangana, India

Status

Not yet recruiting

Address

Gandhi Hospital

Telangana, , 500003

Soroka Medical Center, Beer Sheva, Israel

Status

Recruiting

Address

Soroka Medical Center

Beer Sheva, , 8410101

Galilee Medical Center - Internal A, Nahariya, Israel

Status

Recruiting

Address

Galilee Medical Center - Internal A

Nahariya, , 22100

Kaplan Medical Center, Rehovot, Israel

Status

Recruiting

Address

Kaplan Medical Center

Rehovot, , 7610001

Fukuoka University Chikushi Hospital, Chikushino, Fukuoka, Japan

Status

Recruiting

Address

Fukuoka University Chikushi Hospital

Chikushino, Fukuoka,

Tokushukai Sapporo Tokushukai Hospital, Sapporo-shi, Hokkaido, Japan

Status

Recruiting

Address

Tokushukai Sapporo Tokushukai Hospital

Sapporo-shi, Hokkaido, 004 0041

Sapporo Medical University Hospital, Sapporo, Hokkaido, Japan

Status

Recruiting

Address

Sapporo Medical University Hospital

Sapporo, Hokkaido,

Infusion Clinic, Osaka-shi, Osaka-Fu, Japan

Status

Recruiting

Address

Infusion Clinic

Osaka-shi, Osaka-Fu, 530-0011

Sai Gastroenterologist Proctology, Fujiidera, Osaka, Japan

Status

Completed

Address

Sai Gastroenterologist Proctology

Fujiidera, Osaka, 583-0027

Matsuda Hospital, Hamamatsu-shi, Shizuoka-Ken, Japan

Status

Recruiting

Address

Matsuda Hospital

Hamamatsu-shi, Shizuoka-Ken, 4328061

Shinjuku-ku, Tokyo-To, Japan

Status

Recruiting

Address

Center Hospital of the National Center for Global Health and Medicine

Shinjuku-ku, Tokyo-To, 162 8655

Showa University Koto Toyosu Hospital, Koto-ku, Tokyo, Japan

Status

Recruiting

Address

Showa University Koto Toyosu Hospital

Koto-ku, Tokyo, 135 8577

Kyorin University Hospital, Mitaka, Tokyo, Japan

Status

Recruiting

Address

Kyorin University Hospital

Mitaka, Tokyo, 181-8611

Fukuoka University Hospital, Fukuoka, Japan

Status

Completed

Address

Fukuoka University Hospital

Fukuoka, , 814-0180

Sameshima Hospital, Kagoshima, Japan

Status

Recruiting

Address

Sameshima Hospital

Kagoshima, , 892-0846

Toyama Prefectural Central Hospital, Toyama, Japan

Status

Completed

Address

Toyama Prefectural Central Hospital

Toyama, , 930-8550

Yamagata University Hospital, Yamagata, Japan

Status

Recruiting

Address

Yamagata University Hospital

Yamagata, , 990-9585

Ajou University Hospital, Suwon-si, Gyeonggi-do, Korea, Republic of

Status

Recruiting

Address

Ajou University Hospital

Suwon-si, Gyeonggi-do, 443380

Samsung Medical Center, Seoul, Korea, Korea, Republic of

Status

Recruiting

Address

Samsung Medical Center

Seoul, Korea, 06351

Seoul St. Mary's Hospital, Seoul, Korea, Korea, Republic of

Status

Recruiting

Address

Seoul St. Mary's Hospital

Seoul, Korea, 06591

Inje University Haeundae Paik Hospital, Busan, Korea, Republic of

Status

Completed

Address

Inje University Haeundae Paik Hospital

Busan, , 48108

Gangwon-do, Korea, Republic of

Status

Completed

Address

Yonsei University Wonju Severance Christian Hospital

Gangwon-do, , 26426

Riga, Rīga, Latvia

Status

Recruiting

Address

Pauls Stradins Clinical Univeristy Hospital

Riga, Rīga, LV-1002

Riga, Rīga, Latvia

Status

Recruiting

Address

Pauls Stradins Clinical Univeristy Hospital

Riga, Rīga, LV-1002

NZOZ Vivamed, Warsaw, Mazowieckie, Poland

Status

Recruiting

Address

NZOZ Vivamed

Warsaw, Mazowieckie, 03-580

Szpital Miejski Sw. Jana Pawla II, Elblag, Poland

Status

Completed

Address

Szpital Miejski Sw. Jana Pawla II

Elblag, , 82-300

WIP Warsaw IBD Point Profesor Kierkus, Warszawa, Poland

Status

Completed

Address

WIP Warsaw IBD Point Profesor Kierkus

Warszawa, , 00-728

ETG Zamość, Zamosc, Poland

Status

Active, not recruiting

Address

ETG Zamość

Zamosc, , 22-400

SC Pelican SRL, Oradea, Bihor, Romania

Status

Recruiting

Address

SC Pelican SRL

Oradea, Bihor, 410469

SC Med Life SA, Bucuresti, Romania

Status

Recruiting

Address

SC Med Life SA

Bucuresti, , 010719

SC Centrul Medical Sana SRL, Bucuresti, Romania

Status

Recruiting

Address

SC Centrul Medical Sana SRL

Bucuresti, , 011025

Spital Clinic Colentina, Bucuresti, Romania

Status

Recruiting

Address

Spital Clinic Colentina

Bucuresti, ,

Spitalul Clinic Judetean de Urgenta Cluj, Cluj-Napoca, Romania

Status

Recruiting

Address

Spitalul Clinic Judetean de Urgenta Cluj

Cluj-Napoca, , 400006

S.C. Materna Care S.R.L., Timisoara, Romania

Status

Recruiting

Address

S.C. Materna Care S.R.L.

Timisoara, , 300645

Olla-Med, Moscow, Moskva, Russian Federation

Status

Completed

Address

Olla-Med

Moscow, Moskva, 105554

Novosibirski Gastrocenter, Novosibirsk, Novosibirskaya Oblast', Russian Federation

Status

Completed

Address

Novosibirski Gastrocenter

Novosibirsk, Novosibirskaya Oblast', 630007

Rostov State Medical University, Rostov-on-Don, Rostovskaya Oblast', Russian Federation

Status

Completed

Address

Rostov State Medical University

Rostov-on-Don, Rostovskaya Oblast', 344091

Moscow, Russian Federation

Status

Completed

Address

Open Joint Stock Company Clinical and Diagnostic Center Euromedservice

Moscow, ,

The University Clinic of OSMU, Omsk, Russian Federation

Status

Completed

Address

The University Clinic of OSMU

Omsk, , 644050

SPb SBIH "City Mariinskaya Hospital", Saint-Petersburg, Russian Federation

Status

Completed

Address

SPb SBIH "City Mariinskaya Hospital"

Saint-Petersburg, , 194104

St. Petersburg, Russian Federation

Status

Completed

Address

GOU VPO St-Petersburg SMA n/a Mechnikov Fed. Agen of Health

St. Petersburg, , 195067

FNsP FDRoosevelta Banska Bystrica, Banska Bystrica, Slovakia

Status

Recruiting

Address

FNsP FDRoosevelta Banska Bystrica

Banska Bystrica, , 97517

ENDOMED s.r.o., Kosice, Slovakia

Status

Recruiting

Address

ENDOMED s.r.o.

Kosice, , 04013

Kiev, Kyiv, Ukraine

Status

Recruiting

Address

Medical Center of Limited Liability Company "Medical Center "Consilium Medical"

Kiev, Kyiv, 4050

Lviv Railway Clinical Hospital, Lviv, Lvivska Oblast, Ukraine

Status

Recruiting

Address

Lviv Railway Clinical Hospital

Lviv, Lvivska Oblast, 79000

Lviv Regional Endocrinology Dispensary, Lviv, Lvivska Oblast, Ukraine

Status

Recruiting

Address

Lviv Regional Endocrinology Dispensary

Lviv, Lvivska Oblast, 79000

Dnipro, Ukraine

Status

Recruiting

Address

Medical Center of LLC Medical Center Clinic of Family Medicine

Dnipro, ,

Kyiv, Ukraine

Status

Recruiting

Address

International Institute of Clinical Trials LLC

Kyiv, , 02091

Odesa, Ukraine

Status

Recruiting

Address

Communal Enterprise "Odesa Regional Clinical Hospital"

Odesa, , 65000

Uzhgorod, Ukraine

Status

Recruiting

Address

A. Novak Transcarpathian Regional Clinical Hospital

Uzhgorod, , 88018

Vinnytsia, Ukraine

Status

Recruiting

Address

CCH #1 Vinnytsia M.I. Pyrogov NMU Ch of Propaedeutics of IM

Vinnytsia, , 21029

Vinnytsia, Ukraine

Status

Recruiting

Address

Vinnytsia War Veterans Regional Clinical Hospital

Vinnytsia, ,

Diacenter LLC, Zaporizhzhia, Ukraine

Status

Recruiting

Address

Diacenter LLC

Zaporizhzhia, , 69076

Royal Derby Hospital, Derby, Derbyshire, United Kingdom

Status

Recruiting

Address

Royal Derby Hospital

Derby, Derbyshire, DE22 3NE

Whipps Cross University Hospital, Leytonstone, London, United Kingdom

Status

Recruiting

Address

Whipps Cross University Hospital

Leytonstone, London, E11 1NR

Guys/St. Thomas Hospital, London, Surrey, United Kingdom

Status

Recruiting

Address

Guys/St. Thomas Hospital

London, Surrey, SE1 9RT

St. George's Hospital, London, United Kingdom

Status

Recruiting

Address

St. George's Hospital

London, , SW17 0QT

York Hospital, York, United Kingdom

Status

Recruiting

Address

York Hospital

York, , YO31 8HE

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